Protein Domain : IPR027131

Type:  Family Name:  Structural maintenance of chromosomes protein 5
Description:  SMC5 is a core component of the SMC5-SMC6 complex [, ], a complex involved in repair of DNA double-strand breaks by homologous recombination [, ]. In humans, the SMC5-SMC6 complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks []. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs) []. SMC5 is required for sister chromatid cohesion during prometaphase and mitotic progression; the function seems to be independent of SMC6 []. Short Name:  SMC5
Paste the following link

0 Child Features

0 Contains

1 Cross References

Identifier
PTHR19306:SF1

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0000724 IPR027131
GO:0006281 IPR027131
GO:0030915 IPR027131

3 Ontology Annotations

GO Term Gene Name
GO:0000724 IPR027131
GO:0006281 IPR027131
GO:0030915 IPR027131

0 Parent Features

671 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
174036 D8RT69 PAC:15414732 Selaginella moellendorffii 1028  
evm.model.supercontig_125.40 PAC:16407271 Carica papaya 1015  
29864.m001445 B9RVK1 PAC:16811757 Ricinus communis 1057  
Cucsa.128150.1 PAC:16962131 Cucumis sativus 849  
Cucsa.128160.1 PAC:16962132 Cucumis sativus 179  
orange1.1g001581m A0A067GXB7 PAC:18102142 Citrus sinensis 1050  
orange1.1g001573m A0A067H6Y3 PAC:18102141 Citrus sinensis 1051  
AT5G15920.1 Q9LFS8 PAC:19672893 Arabidopsis thaliana 1053  
Thhalv10012535m V4N7G6 PAC:20206712 Eutrema salsugineum 1052  
Ciclev10030582m V4TFV4 PAC:20804301 Citrus clementina 1051  
Lus10039590 PAC:23165005 Linum usitatissimum 1027  
Lus10005338 PAC:23154595 Linum usitatissimum 147  
Lus10029476 PAC:23149378 Linum usitatissimum 1049  
Potri.001G262600.4 PAC:27042664 Populus trichocarpa 791  
Potri.001G262600.2 PAC:27042663 Populus trichocarpa 974  
Potri.001G262600.3 PAC:27042662 Populus trichocarpa 979  
Potri.001G262600.1 A0A2K2C403 PAC:27042661 Populus trichocarpa 1057  
Gorai.013G183900.1 A0A0D2W7A6 PAC:26789251 Gossypium raimondii 1051  
Gorai.013G183900.2 A0A0D2VFH6 PAC:26789252 Gossypium raimondii 984  
38827 I0Z8T4 PAC:27389338 Coccomyxa subellipsoidea C-169 1074  
163278 C1N4Q2 PAC:27339950 Micromonas pusilla CCMP1545 1089  
85826 C1FGZ7 PAC:27397470 Micromonas sp RCC299 1077  
29255 A4RS60 PAC:27417824 Ostreococcus lucimarinus 1076  
Thecc1EG025515t1 A0A061EZQ7 PAC:27424260 Theobroma cacao 1051  
Migut.B01270.1.p A0A022QKL1 PAC:28947004 Mimulus guttatus 1052  
Migut.B01270.2.p A0A022QKL1 PAC:28947005 Mimulus guttatus 1052  
Araha.27704s0003.1.p PAC:28840798 Arabidopsis halleri 1053  
Cagra.6845s0036.1.p PAC:28894098 Capsella grandiflora 1052  
Glyma.20G198300.1.p I1NHX5 PAC:30520144 Glycine max 1052  
Brara.C00699.1.p A0A397ZSS6 PAC:30615774 Brassica rapa FPsc 1049  

7 Publications

First Author Title Year Journal Volume Pages PubMed ID
            15738391
            19502785
            16810316
            17589526
            10747036
            15010319
            18086888