3 Ontology Annotations
GO Term | Gene Name |
---|---|
GO:0019789 | IPR026846 |
GO:0000724 | IPR026846 |
GO:0030915 | IPR026846 |
Type: | Family | Name: | E3 SUMO-protein ligase Nse2 (Mms21) |
Description: | This entry consists of the E3 SUMO-protein ligase Nse2 (also known as Mms21). Nse2 is an E3 SUMO-protein ligase component of the SMC5-SMC6 complex [, ]. Nse2 acts as an E3 ligase targeting several proteins for sumoylation and is required for efficient DNA repair and maintenance of genome stability [, , , ]. Nse2 and SMC5 may also be required for sister chromatid cohesion during prometaphase and mitotic progression; this role is apparently independent of SMC6 []. Nse2 is necessary for normal cell cycle progression in Arabidopsis, where Nse2 mutation results in abnormal root development []. | Short Name: | Nse2(Mms21) |
GO Term | Gene Name |
---|---|
GO:0019789 | IPR026846 |
GO:0000724 | IPR026846 |
GO:0030915 | IPR026846 |