1 Child Features
DB identifier | Type | Name |
---|---|---|
IPR006909 | Domain | Rad21/Rec8-like protein, C-terminal, eukaryotic |
Type: | Domain | Name: | Rad21/Rec8-like protein, C-terminal |
Description: | This domain represents a conserved C-terminal region found in eukaryotic cohesins of the Rad21, Rec8 and Scc1 families as well as in bacterial segregation and condensation proteins. Rad21/Rec8 like proteins mediate sister chromatid cohesion during mitosis and meiosis, as part of the cohesin complex []. Cohesion is necessary for homologous recombination (including double-strand break repair) and correct chromatid segregation. These proteins may also be involved in chromosome condensation. Dissociation at the metaphase to anaphase transition causes loss of cohesion and chromatid segregation []. | Short Name: | Rad21/Rec8_C |
DB identifier | Type | Name |
---|---|---|
IPR006909 | Domain | Rad21/Rec8-like protein, C-terminal, eukaryotic |