Protein Domain : IPR011537

Type:  Family Name:  NADH ubiquinone oxidoreductase, F subunit
Description:  NADH:ubiquinone oxidoreductase (complex I) () is a respiratory-chain enzyme that catalyses the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane (NADH + ubiquinone = NAD+ + ubiquinol) []. Complex I is a major source of reactive oxygen species (ROS) that are predominantly formed by electron transfer from FMNH(2). Complex I is found in bacteria, cyanobacteria (as a NADH-plastoquinone oxidoreductase), archaea [], mitochondria, and in the hydrogenosome, a mitochondria-derived organelle. In general, the bacterial complex consists of 14 different subunits, while the mitochondrial complex contains homologues to these subunits in addition to approximately 31 additional proteins []. This entry describes the F subunit of complexes that resemble NADH-quinone oxidoreductases. The electron acceptor is a quinone, ubiquinone, in mitochondria and most bacteria, including Escherichia coli, where the recommended gene symbol is nuoF. This family does not have any members in chloroplast or cyanobacteria, where the quinone may be plastoquinone and NADH may be replaced by NADPH, nor in Methanosarcina, where NADH is replaced by F420H2. Short Name:  NADH-UbQ_OxRdtase_suF
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0 Child Features

4 Contains

DB identifier Type Name
IPR019575 Domain NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain
IPR019554 Domain Soluble ligand binding domain
IPR011538 Domain NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain
IPR001949 Conserved_site NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site

1 Cross References

Identifier
TIGR01959

0 Found In

5 GO Annotations

GO Term Gene Name
GO:0010181 IPR011537
GO:0016651 IPR011537
GO:0051287 IPR011537
GO:0051539 IPR011537
GO:0055114 IPR011537

5 Ontology Annotations

GO Term Gene Name
GO:0010181 IPR011537
GO:0016651 IPR011537
GO:0051287 IPR011537
GO:0051539 IPR011537
GO:0055114 IPR011537

0 Parent Features

539 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
150347 D8RVL7 PAC:15413252 Selaginella moellendorffii 460  
evm.model.supercontig_257.6 PAC:16414990 Carica papaya 486  
29929.m004691 B9RMI6 PAC:16813930 Ricinus communis 486  
Cucsa.337250.1 A0A0A0LFB0 PAC:16978577 Cucumis sativus 486  
Cucsa.337250.2 A0A0A0LFB0 PAC:16978578 Cucumis sativus 486  
Cucsa.337250.3 A0A0A0LFB0 PAC:16978579 Cucumis sativus 486  
orange1.1g011427m A0A067GTE7 PAC:18101515 Citrus sinensis 486  
orange1.1g011421m A0A067GTE7 PAC:18101517 Citrus sinensis 486  
orange1.1g011413m A0A067GTE7 PAC:18101516 Citrus sinensis 486  
orange1.1g011433m A0A067GTE7 PAC:18101518 Citrus sinensis 486  
AT5G08530.1 Q9FNN5 PAC:19666391 Arabidopsis thaliana 486  
Thhalv10013394m V4N5M4 PAC:20205177 Eutrema salsugineum 486  
Thhalv10013698m V4KS86 PAC:20205178 Eutrema salsugineum 407  
Ciclev10033600m V4STZ4 PAC:20804568 Citrus clementina 454  
Potri.010G057400.3 B9HTA1 PAC:26980076 Populus trichocarpa 485  
Potri.010G057400.4 B9HTA1 PAC:26980078 Populus trichocarpa 485  
Potri.010G057400.1 B9HTA1 PAC:26980079 Populus trichocarpa 485  
Potri.010G057400.2 B9HTA1 PAC:26980077 Populus trichocarpa 485  
Gorai.001G109800.4 A0A0D2QNP6 PAC:26824424 Gossypium raimondii 486  
Gorai.001G109800.1 A0A0D2QNP6 PAC:26824421 Gossypium raimondii 486  
Gorai.001G109800.2 A0A0D2QNP6 PAC:26824422 Gossypium raimondii 486  
Gorai.001G109800.3 A0A0D2QNP6 PAC:26824423 Gossypium raimondii 486  
Gorai.008G164400.2 A0A0D2PVZ3 PAC:26813970 Gossypium raimondii 486  
Gorai.008G164400.1 A0A0D2RGI6 PAC:26813969 Gossypium raimondii 493  
22252 I0Z5X2 PAC:27390325 Coccomyxa subellipsoidea C-169 467  
204528 C1MSP1 PAC:27341953 Micromonas pusilla CCMP1545 468  
94594 C1E997 PAC:27402094 Micromonas sp RCC299 441  
43184 A4S734 PAC:27419655 Ostreococcus lucimarinus 449  
Thecc1EG010782t1 A0A061E919 PAC:27464475 Theobroma cacao 486  
Migut.E00031.1.p A0A022RQ24 PAC:28920865 Mimulus guttatus 487  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1470679
            10940377
            18394423