Type: | Domain | Name: | WPP domain |
Description: | The WPP domain is thought to be exclusively found in plants. The WPP stands for a tryptophan-proline-proline motif that is highly conserved in the domain []. The WPP domain is known to direct RanGAP (Ran GTPase-activating protein) to the nuclear envelope []. RanGAP is an accessory protein for the small signaling GTPase Ran, which is involved in nucleocytoplasmic transport. Non-RanGAP nuclear envelope proteins are also known to encode WPP domains, such as MFP1 attachment factor 1 (MAF1) [], WPP1 [] and WPP2 []. | Short Name: | WPP_dom |