3 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0000150 | IPR006119 |
| GO:0003677 | IPR006119 |
| GO:0006310 | IPR006119 |
| Type: | Domain | Name: | Resolvase, N-terminal catalytic domain |
| Description: | Site-specific recombination plays an important role in DNA rearrangement in prokaryotic organisms. Two types of site-specific recombination are known to occur:Recombination between inverted repeats resulting in the reversal of a DNA segment.Recombination between repeat sequences on two DNA molecules resulting in their cointegration, or between repeats on one DNA molecule resulting in the excision of a DNA fragment.Site-specific recombination is characterised by a strand exchange mechanism that requires no DNA synthesis or high energy cofactor; the phosphodiester bond energy is conserved in a phospho-protein linkage during strand cleavage and re-ligation.Two unrelated families of recombinases are currently known []. The first, called the 'phage integrase' family, groups a number of bacterial phage and yeast plasmid enzymes. The second [], called the 'resolvase' family, groups enzymes which share the following structural characteristics: an N-terminal catalytic and dimerization domain that contains a conserved serine residue involved in the transient covalent attachment to DNA, and a C-terminal helix-turn-helix DNA-binding domain . The N-terminal resolvase/invertase-type recombinase catalytic domain has an AlphaBeta fold and consists of a five-stranded mixed beta-sheet surrounded bythree alpha helices on one side and one helix on the other []. | Short Name: | Resolv_N |
| GO Term | Gene Name |
|---|---|
| GO:0000150 | IPR006119 |
| GO:0003677 | IPR006119 |
| GO:0006310 | IPR006119 |
