| Type: | Family | Name: | Transcription initiation factor TFIID, 23-30kDa subunit |
| Description: | Transcription initiation factor TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activatorsand repressors. The complex includes TATA binding protein (TBP) and various TBP-associated factors (TAFS). TFIID a bona fide RNA polymerase II-specificTATA-binding protein-associated factor (TAF) and is essential for viability [].TFIID acts to nucleate the transcription complex, recruiting the rest of the factors through a direct interaction with TFIIB. The TBP subunit of TFIID is sufficient for TATA-element binding and TFIIB interaction, and can support basal transcription. The protein belongs to the TAF2H family. | Short Name: | TFIID_30kDa |
