Protein Domain : IPR002467

Type:  Family Name:  Peptidase M24A, methionine aminopeptidase, subfamily 1
Description:  This group of metallopeptidases belong to MEROPS peptidase family M24 (clan MG), subfamily M24A.Methionine aminopeptidase () (MAP) catalyses the hydrolytic cleavage of the N-terminal methionine from newly synthesised polypeptides if the penultimate amino acid is small, with different tolerance to Val and Thr at this position []. All MAP studied to date are monomeric proteins that require cobalt ions for activity. Two subfamilies of MAP enzymes are known to exist [, ]. While being evolutionary related, they only share a limited amount of sequence similarity, mostly clustered around the residues shown to be involved in cobalt-binding in Escherichia coli MAP []. Subfamily 1 consists of enzymes from prokaryotes as well as eukaryotic MAP-1, while the second group () is made up of archaeal MAP and eukaryotic MAP-2. Short Name:  Pept_M24A_MAP1
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0 Child Features

0 Contains

3 Cross Referencess

Identifier
PS00680
TIGR00500
MF_01974

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0004177 IPR002467
GO:0008235 IPR002467
GO:0006508 IPR002467

3 Ontology Annotations

GO Term Gene Name
GO:0004177 IPR002467
GO:0008235 IPR002467
GO:0006508 IPR002467

1 Parent Features

DB identifier Type Name
IPR001714 Family Peptidase M24, methionine aminopeptidase

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
270346 D8QXE1 PAC:15419528 Selaginella moellendorffii 343  
106561 D8S1N6 PAC:15418653 Selaginella moellendorffii 401  
117647 D8SIG7 PAC:15407044 Selaginella moellendorffii 291  
439350 D8R3S9 PAC:15423232 Selaginella moellendorffii 322  
evm.model.supercontig_1.217 PAC:16404141 Carica papaya 201  
evm.model.supercontig_55.168 PAC:16422559 Carica papaya 348  
evm.model.supercontig_611.1 PAC:16423881 Carica papaya 256  
29738.m001052 B9SEJ2 PAC:16807342 Ricinus communis 365  
30115.m001180 B9SC40 PAC:16817960 Ricinus communis 282  
30174.m008848 B9RD92 PAC:16822493 Ricinus communis 397  
Cucsa.366850.1 PAC:16981558 Cucumis sativus 352  
Cucsa.383430.1 PAC:16982369 Cucumis sativus 369  
Cucsa.257500.2 PAC:16972716 Cucumis sativus 355  
Cucsa.257500.3 PAC:16972717 Cucumis sativus 314  
Cucsa.257500.1 A0A0A0L6G2 PAC:16972715 Cucumis sativus 402  
orange1.1g021683m A0A067GI27 PAC:18125276 Citrus sinensis 309  
orange1.1g021967m A0A067GVE2 PAC:18125277 Citrus sinensis 304  
orange1.1g021992m A0A067GVE2 PAC:18125278 Citrus sinensis 304  
orange1.1g026622m A0A067GV26 PAC:18125282 Citrus sinensis 235  
orange1.1g026698m A0A067GV26 PAC:18125283 Citrus sinensis 235  
orange1.1g026636m A0A067GV26 PAC:18125284 Citrus sinensis 235  
orange1.1g018617m A0A067GV15 PAC:18125273 Citrus sinensis 353  
orange1.1g020322m A0A067GHS7 PAC:18125274 Citrus sinensis 327  
orange1.1g020521m A0A067GI21 PAC:18125275 Citrus sinensis 325  
orange1.1g017786m A0A067G3N0 PAC:18121843 Citrus sinensis 366  
orange1.1g021513m A0A067G308 PAC:18121844 Citrus sinensis 311  
orange1.1g021989m A0A067FRW3 PAC:18121845 Citrus sinensis 304  
orange1.1g018846m PAC:18136051 Citrus sinensis 349  
orange1.1g018913m PAC:18136052 Citrus sinensis 349  
orange1.1g018857m PAC:18136054 Citrus sinensis 349  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            8471602
            7644482
            8772380
            20521764