1 Found In
DB identifier | Type | Name |
---|---|---|
IPR017415 | Family | RNA polymerase II transcriptional coactivator KELP |
Type: | Domain | Name: | DEK, C-terminal |
Description: | DEK is a chromatin associated protein that is linked with cancers and autoimmune disease. This domain is found at the C-terminal of DEK and is of clinical importance since it can reverse the characteristic abnormal DNA-mutagen sensitivity in fibroblasts from ataxia-telangiectasia (A-T) patients []. The structure of this domain shows it to be homologous to the E2F/DP transcription factor family []. This domain is also found in chitin synthase proteins like , and in protein phosphatases such as . | Short Name: | DEK_C |
DB identifier | Type | Name |
---|---|---|
IPR017415 | Family | RNA polymerase II transcriptional coactivator KELP |