Protein Domain : IPR011821

Type:  Family Name:  O-succinylhomoserine (thiol)-lyase
Description:  This family consists of O-succinylhomoserine (thiol)-lyase, one of three different enzymes designated cystathionine gamma-synthase and involved in methionine biosynthesis. In all three cases, sulphur is added by transsulphuration from Cys to yield cystathionine rather than by a sulphhydrylation step that uses H2S directly and bypasses cystathionine. The CGS enzyme () from Escherichia coliis, like other CGS enzymes, a homotetramer composed of two catalytically active dimers []. The active site of each dimer is found at the interface between the monomers and involves residues from each monomer. Catalysis occurs by alpha,gamma-elimination/replacement reactions. Short Name:  O_succ_thio_ly
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0 Child Features

2 Contains

DB identifier Type Name
IPR015421 Domain Pyridoxal phosphate-dependent transferase, major region, subdomain 1
IPR015422 Domain Pyridoxal phosphate-dependent transferase, major region, subdomain 2

1 Cross References

Identifier
TIGR02080

0 Found In

0 GO Annotation

0 Ontology Annotations

1 Parent Features

DB identifier Type Name
IPR000277 Family Cys/Met metabolism, pyridoxal phosphate-dependent enzyme

4 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Brdisv1pangenome1006479m.p PAC:33599115 Brachypodium distachyon Pangenome 368  
Brdisv1pangenome1009768m.p PAC:33640405 Brachypodium distachyon Pangenome 386  
Brdisv1BdTR11A1040703m.p PAC:35691557 Brachypodium distachyon BdTR11a 386  
Brdisv1BdTR11A1041320m.p PAC:35696177 Brachypodium distachyon BdTR11a 368  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9843488