Protein Domain : IPR017785

Type:  Family Name:  Choline-sulfatase
Description:  This entry consists of known and predicted choline-sulphatase enzymes involved in the synthesis of glycine betaine from choline [, ]. The symbiotic soil bacterium Rhizobium melilotican synthesise glycine betaine from choline-O-sulphate and choline to protect itself from osmotic stress [, ]. Glycine betaine biosynthesis is not, however, crucial for nodulation and nitrogen fixation. This biosynthetic pathway is encoded by the betICBA locus, which comprises a regulatory gene, betI, and three structural genes, betC (choline sulphatase), betB (betaine aldehyde dehydrogenase), and betA (choline dehydrogenase). betICBA genes constitute a single operon, despite the existence of intergenic regions that contain mosaic elements between betI and betC, and between betB and betA []. betC lies adjacent to an ATP-binding cassette transporter and a LysR type regulator, but well away from betBA, in this species []. Short Name:  Choline-sulfatase
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0 Child Features

2 Contains

DB identifier Type Name
IPR017849 Domain Alkaline phosphatase-like, alpha/beta/alpha
IPR000917 Domain Sulfatase

1 Cross References

Identifier
TIGR03417

0 Found In

0 GO Annotation

0 Ontology Annotations

0 Parent Features

4 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Brdisv1pangenome1007520m.p PAC:33657431 Brachypodium distachyon Pangenome 504  
Brdisv1pangenome1009148m.p PAC:33624155 Brachypodium distachyon Pangenome 405  
Brdisv1BdTR11A1045732m.p PAC:35693669 Brachypodium distachyon BdTR11a 405  
Brdisv1BdTR11A1042459m.p PAC:35692288 Brachypodium distachyon BdTR11a 504  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9141699
            9736747
            12906115
            17116241