Protein Domain : IPR027362

Type:  Domain Name:  DNA topoisomerase I catalytic fragment, domain 2
Description:  Type I topoisomerases (type IB isomerases) relax positive and negative supercoils and are very important in DNA replication. The C-terminal segment of this enzyme constitutes the catalytic domain. The catalytic domain contains five amino acids, conserved in all eukaryotic type IB topoisomerases. Its structure consists of ten alpha helices and a three-strand beta sheet, and resembles the catalytic domains of site-specific recombinases that act via a topoisomerase IB-like mechanism [].This entry represents the carboxyl lobe of the catalytic domain (domain 2), and consists of four alpha-helices (helices 6-10). Short Name:  TopoI_cat_dom2
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0 Child Features

0 Contains

1 Cross References

Identifier
G3DSA:1.20.120.380

0 Found In

0 GO Annotation

0 Ontology Annotations

0 Parent Features

67 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Lus10015916 PAC:23143802 Linum usitatissimum 324  
55875 C1DYP1 PAC:27396745 Micromonas sp RCC299 1091  
Glyma.15G252400.1.p A0A0R0G612 PAC:30498786 Glycine max 86  
evm_27.model.AmTr_v1.0_scaffold00004.278 W1NDM1 PAC:31550342 Amborella trichopoda 500  
evm_27.model.AmTr_v1.0_scaffold00041.270 W1PZE6 PAC:31559551 Amborella trichopoda 116  
evm_27.model.AmTr_v1.0_scaffold00063.97 U5D248 PAC:31569072 Amborella trichopoda 276  
Manes.02G012600.1.p A0A2C9WBE8 PAC:32333665 Manihot esculenta 1802  
Phvul.005G047400.2.p PAC:37152380 Phaseolus vulgaris 299  
Phvul.005G047400.1.p V7BVV5 PAC:37152379 Phaseolus vulgaris 322  
Zm00008a008211_P01 PAC:37203358 Zea mays PH207 155  
PGSC0003DMP400019204 PAC:37450370 Solanum tuberosum 244  
Pavir.J345900.1.p PAC:37678622 Panicum virgatum 364  
Gohir.A10G020100.1.p PAC:38095802 Gossypium hirsutum 465  
SbRio.04G373400.1.p PAC:39012104 Sorghum bicolor Rio 422  
Vigun01g056600.1.p PAC:39049980 Vigna unguiculata 335  
Lesat.0034s0228.1.p PAC:39458190 Lepidium sativum 144  
Lesat.0041s0290.1.p PAC:39451749 Lepidium sativum 189  
Pahal.9G037600.1.p A0A2S3IGV6 PAC:40359018 Panicum hallii 932  
PhHAL.9G036200.1.p PAC:40398692 Panicum hallii HAL 932  
PhHAL.9G036200.2.p PAC:40398693 Panicum hallii HAL 817  
Misin09G097800.1.p PAC:40480339 Miscanthus sinensis 330  
Thint.02G0181100.1.p PAC:40777949 Thinopyrum intermedium 489  
Solyc12g068070.2.1 PAC:41481726 Solanum lycopersicum 689  
Pavir.1NG112276.1.p PAC:41582476 Panicum virgatum 364  
Manes.02G012600.2.p A0A2C9WBE8 PAC:41879804 Manihot esculenta 1802  
Manes.02G012600.3.p A0A2C9WBE8 PAC:41879805 Manihot esculenta 1802  
Sphmag01G147700.1.p PAC:41933963 Sphagnum magellanicum 339  
Thecc.05G239400.10.p A0A061F0J5 PAC:42029096 Theobroma cacao 384  
Thecc.05G239400.11.p A0A061F0J5 PAC:42029097 Theobroma cacao 384  
Thecc.05G239400.9.p A0A061F0J5 PAC:42029095 Theobroma cacao 384  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9529259