Type: | Domain | Name: | Chemokine-binding M3, subdomain 2, viral |
Description: | This entry represents a beta-sandwich domain found in a group of viral chemokine binding proteins. These proteins bind with CC-chemokine MCP-1, acting as cytokine decoy receptors []. For example, the murine herpesvirus decoy receptor M3 acts as an immune system saboteur by altering host anti-viral inflammatory repsonses. M3 adopts a structure consisting of two different beta-sandwich domains of partial topological similarity to immunoglobulin-like folds. | Short Name: | Chemokine-bd_M3_sub2_vir |