Protein Domain : IPR009428

Type:  Domain Name:  Beta-catenin-interacting ICAT
Description:  This domain is characteristic of eukaryotic beta-catenin-interacting (ICAT) proteins. Beta-catenin is a multifunctional protein involved in both cell adhesion and transcriptional activation. Transcription mediated by the beta-catenin/Tcf complex is involved in embryological development and is upregulated in various cancers. ICAT selectively inhibits beta-catenin/Tcf binding in vivo, without disrupting beta-catenin/cadherin interactions [].Protein LZIC contains a leucine zipper domain and an ICAT homologous domain, with particular conservation of residues that are used by ICAT for beta-catenin-binding [, ]. Short Name:  ICAT
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0 Child Features

0 Contains

3 Cross Referencess

Identifier
PF06384
G3DSA:1.10.10.490
SSF81730

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0008013 IPR009428

1 Ontology Annotations

GO Term Gene Name
GO:0008013 IPR009428

0 Parent Features

77 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Potri.015G002700.1 A0A2K1XFT8 PAC:27018253 Populus trichocarpa 34  
Potri.015G133000.1 PAC:27019557 Populus trichocarpa 196  
8270 A4RWF9 PAC:27415275 Ostreococcus lucimarinus 157  
Migut.D00396.1.p PAC:28928324 Mimulus guttatus 734  
Brara.K01487.1.p A0A397L3S0 PAC:30646860 Brassica rapa FPsc 140  
Medtr7g017660.1 G7KS20 PAC:31077353 Medicago truncatula 82  
Traes_7AS_4946983A4.2 PAC:31905014 Triticum aestivum 145  
Traes_7BS_09D0DE0F5.1 PAC:31858654 Triticum aestivum 270  
Traes_7BS_09D0DE0F5.3 PAC:31858653 Triticum aestivum 275  
Traes_7BS_09D0DE0F5.2 PAC:31858652 Triticum aestivum 281  
Traes_7DS_4D83F4BCD.1 PAC:31821284 Triticum aestivum 235  
Manes.05G154300.1.p A0A2C9VZ05 PAC:32337140 Manihot esculenta 361  
Manes.09G088100.1.p A0A2C9VAJ2 PAC:32339915 Manihot esculenta 221  
Aqcoe4G024200.1.p PAC:33067850 Aquilegia coerulea 178  
Solyc10g078250.1.1 PAC:36154848 Solanum lycopersicum 91  
Solyc09g008630.2.1 PAC:36131939 Solanum lycopersicum 230  
Phvul.006G079900.1.p V7BLN4 PAC:37171516 Phaseolus vulgaris 535  
Potri.015G002700.1.p A0A2K1XFT8 PAC:37253618 Populus trichocarpa 34  
Bol042188 PAC:37362104 Brassica oleracea capitata 143  
AT5G18320.1 Q3E9F7 PAC:37416550 Arabidopsis thaliana 458  
Pavir.5NG352700.1.p PAC:37574873 Panicum virgatum 81  
Sobic.004G135900.1.p A0A194YPK6 PAC:37931336 Sorghum bicolor 80  
VIT_203s0038g03820.1 PAC:38035140 Vitis vinifera 731  
Mamar.0036s0151.1.p PAC:39421172 Malcolmia maritima 458  
Thlar.0008s0484.1.p PAC:39531178 Thlaspi arvense 326  
Camar.0484s0008.1.p PAC:39617126 Cakile maritima 222  
Desop.0007s0074.2.p PAC:39672466 Descurainia sophioides 79  
Clevi.0005s0190.1.p PAC:39718760 Cleome violacea 504  
Clevi.0085s0033.1.p PAC:39723606 Cleome violacea 357  
Ibeam.8761s0001.1.p PAC:39761420 Iberis amara 452  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12408824
            11712074
            15932753