| Type: | Domain | Name: | Helicase/SANT-associated domain |
| Description: | The helicase/SANT-associated (HSA) domain is a predicted DNA-binding domain of ~75 amino acids [], which is found in the eukaryotic SRCAP/p400/DOM and SNF2/brahma families []. While each family has the core sequences that define the HSA domain, they each also have additional sequences that distinguish these families from one another. For example, the sequence HWDY(L/C)EEEM(Q/V) is found in the SRCAP/p400/DOM family, whereas the sequence HQE(Y/F)LNSILQ is found in the SNF2 /brahma family []. In addition to the SANT and helicase domains, the HSA domain is also found in association with the bromo domain []. | Short Name: | HSA_dom |
