Protein Domain : IPR014453

Type:  Family Name:  Inhibitor of vertebrate lysozyme
Description:  C-type lysozyme enzymes, such as hen egg white lysozyme (HEWL), provide anti-bacterial activity by cleaving peptidoglycan in Gram-positive bacterial cell walls. In humans, C-type lysozyme is found in all secretions, including tears and saliva. Certain Gram-positive bacteria can produce proteins with anti-lysozyme activity known as Inhibitor of Vertebrate Lysozyme (IVY), which act as virulence factors [, ]. IVY proteins have a 3-layer alpha(2)/beta(5)/alpha(2) topology, and contain a protruding 5-residue loop that is essential for their inhibitory effect []. Short Name:  Ihibitor_vertebrate_lysozyme

0 Child Features

0 Contains

3 Cross Referencess

Identifier
PIRSF009103
G3DSA:3.40.1420.10
SSF89872

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0043086 IPR014453
GO:0042597 IPR014453

2 Ontology Annotations

GO Term Gene Name
GO:0043086 IPR014453
GO:0042597 IPR014453

0 Parent Features

60 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
evm.model.supercontig_101.6 PAC:16404814 Carica papaya 59  
Thhalv10021161m V4NQN9 PAC:20183585 Eutrema salsugineum 316  
Potri.011G139500.3 B9I0F2 PAC:27000757 Populus trichocarpa 208  
Potri.011G139500.5 B9I0F2 PAC:27000758 Populus trichocarpa 208  
Potri.011G139500.1 U5FZT9 PAC:27000754 Populus trichocarpa 241  
Potri.011G139500.4 B9I0F2 PAC:27000756 Populus trichocarpa 208  
Potri.011G139500.2 PAC:27000755 Populus trichocarpa 209  
Potri.011G090400.1 A0A2K1YHL5 PAC:27002497 Populus trichocarpa 74  
Glyma.20G032900.1.p K7N153 PAC:30521695 Glycine max 426  
Traes_2BL_7D6CA68B8.1 PAC:31836696 Triticum aestivum 141  
GSMUA_AchrUn_randomP25660_001 PAC:32295270 Musa acuminata 145  
Sphfalx0176s0024.1.p PAC:32608967 Sphagnum fallax 105  
Brdisv1Bd3-1_r1009472m.p PAC:33313220 Brachypodium distachyon Bd3-1 325  
Brdisv1Bd3-1_r1009471m.p PAC:33313219 Brachypodium distachyon Bd3-1 328  
Brdisv1Gaz-81036403m.p PAC:33824627 Brachypodium distachyon Gaz-8 94  
Brdisv1BdTR11A1048455m.p PAC:35694882 Brachypodium distachyon BdTR11a 718  
Brdisv1BdTR11A1041701m.p PAC:35690098 Brachypodium distachyon BdTR11a 593  
Potri.011G139500.3.p B9I0F2 PAC:37240652 Populus trichocarpa 208  
Potri.011G139500.4.p B9I0F2 PAC:37240653 Populus trichocarpa 208  
Potri.011G139500.1.p U5FZT9 PAC:37240651 Populus trichocarpa 241  
Potri.011G090400.1.p A0A2K1YHL5 PAC:37239546 Populus trichocarpa 74  
Podel.11G136400.1.p PAC:37333018 Populus deltoides WV94 208  
Podel.11G136400.2.p PAC:37333019 Populus deltoides WV94 208  
Bol045917 PAC:37373957 Brassica oleracea capitata 62  
Pavir.2NG164800.1.p PAC:37581940 Panicum virgatum 85  
Pavir.6KG062600.1.p PAC:37694501 Panicum virgatum 89  
Pavir.6KG062600.2.p PAC:37694502 Panicum virgatum 85  
AH010927-RA PAC:38170666 Amaranthus hypochondriacus 472  
Lsat_1_v5_gn_7_43621.1 A0A2J6JRL5 PAC:38911049 Lactuca sativa 105  
Alyli.0145s0074.1.p PAC:39171155 Alyssum linifolium 130  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11278658
            15141308
            17405861