Type: | Family | Name: | Villin-1, plant |
Description: | Villin belongs to the villin/gelsolin family, whose members are actin-modulating proteins that sever F-actin, cap the barbed ends of actin filaments preventing monomer exchange, and promote the nucleation step of actin polymerisation []. Villin is involved in actin remodelling necessary for many cellular processes requiring the actin cytoskeleton plasticity [, ].This entry represents villin-1 (VLN1) from plants, including AtVLN1 (At2g29890) from Arabidopsis []. Arabidopsis contains at least five villin-like genes (AtVLNs) encoding five different VLN isoforms. AtVLN1 bundles actin filaments []. However, unlike human plasma gelsolin, AtVLN1 does not nucleate actin filaments, does not block the polymerisation of profilin-actin onto barbed ends, and does not sever pre-existing filaments []. | Short Name: | Villin-1_plant |