Type: | Domain | Name: | Mycoplasma arthritidis-derived mitogen, N-terminal |
Description: | Mycoplasma arthritidis-derived mitogen (MA-Mit) adopts a completely alpha-helical structure consisting of ten alpha helices arranged in two orthogongal bundles. MA-Mit is a superantigen that can activate large fractions of T cells bearing particular TCR V-beta elements. Two MA-Mit molecules form an asymmetric dimer and cross-link two MHC antigens to form a dimerised MA-Mit-MHC complex []. This entry represents the N-terminal alpha-helical bundle domain. | Short Name: | M_arthritidis-der_mitogen_N |