Protein Domain : IPR001689

Type:  Family Name:  Flagellar motor switch protein FliM
Description:  The flagellar motor switch in Escherichia coliand Salmonella typhimuriumregulates the direction of flagellar rotation and hence controls swimming behaviour []. The switch is a complex apparatus that responds to signals transduced by the chemotaxis sensory signalling system during chemotactic behaviour []. CheY, the chemotaxis response regulator, is believed to act directly on the switch to induce tumbles in the swimming pattern, but no physical interactions of CheY and switch proteins have yet been demonstrated.The switch complex comprises at least three proteins - FliG, FliM and FliN. It has been shown that FliG interacts with FliM, FliM interacts with itself, and FliM interacts with FliN []. Several residues within the middle third of FliG appear to be strongly involved in the FliG-FliM interaction, with residues near the N or C termini being less important []. Such clustering suggests that FliG-FliM interaction plays a central role in switching.Analysis of the FliG, FliM and FliN sequences shows that none are especially hydrophobic or appear to be integral membrane proteins []. This result is consistent with other evidence suggesting that the proteins may be peripheral to the membrane, possibly mounted on the basal body M ring [, ]. Short Name:  Flag_FliM
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0 Child Features

1 Contains

DB identifier Type Name
IPR001543 Domain Surface presentation of antigen (SpoA)

4 Cross Referencess

Identifier
PF02154
PIRSF002888
PR00955
TIGR01397

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0003774 IPR001689
GO:0071973 IPR001689
GO:0009425 IPR001689

3 Ontology Annotations

GO Term Gene Name
GO:0003774 IPR001689
GO:0071973 IPR001689
GO:0009425 IPR001689

0 Parent Features

2 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Brdisv1BdTR11A1045503m.p PAC:35689454 Brachypodium distachyon BdTR11a 641  
Zosma07g02740 PAC:50101912 Zostera marina 521  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            8224881
            2656645
            8631704
            1631122