3 Ontology Annotations
GO Term | Gene Name |
---|---|
GO:0022900 | IPR012576 |
GO:0005739 | IPR012576 |
GO:0005747 | IPR012576 |
Type: | Family | Name: | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 |
Description: | NADH:ubiquinone oxidoreductase (complex I) () is a respiratory-chain enzyme that catalyses the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane (NADH + ubiquinone = NAD+ + ubiquinol) []. Complex I is a major source of reactive oxygen species (ROS) that are predominantly formed by electron transfer from FMNH(2). Complex I is found in bacteria, cyanobacteria (as a NADH-plastoquinone oxidoreductase), archaea [], mitochondria, and in the hydrogenosome, a mitochondria-derived organelle. In general, the bacterial complex consists of 14 different subunits, while the mitochondrial complex contains homologues to these subunits in addition to approximately 31 additional proteins []. This family represents an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain []. | Short Name: | NDUFB3 |
GO Term | Gene Name |
---|---|
GO:0022900 | IPR012576 |
GO:0005739 | IPR012576 |
GO:0005747 | IPR012576 |