1 Found In
| DB identifier | Type | Name |
|---|---|---|
| IPR011177 | Family | Transcription initiation factor TFIID subunit 1, animal |
| Type: | Domain | Name: | TAFII-230 TBP-binding |
| Description: | In eukaryotes, the general transcription factor TFIID helps to regulate transcription by RNA polymerase II from class II promoters. TFIID consists of TATA-box-binding proteins (TBP) and TBP-associated factors (TAFIIs), which together mediate both activation and inhibition of transcription. In Drosophila, the N-terminal region of TAFII-230 (the TFIID 230kDa subunit) binds directly to TBP, thereby inhibiting the binding of TBP to the TATA box. The structure of TAFII-230 is comprised of three short helices in an irregular array, which forms the core that occupies the DNA-binding surface of TBP []. | Short Name: | TAF_II_230-bd |
| DB identifier | Type | Name |
|---|---|---|
| IPR011177 | Family | Transcription initiation factor TFIID subunit 1, animal |
