| Type: | Family | Name: | FAM175 family, plant |
| Description: | Members of protein family FAM175 include the BRCA1-A complex subunit Abraxas [, ], BRISC complex subunit Abro1 (Abraxas brother protein 1) [, ], and uncharacterised plant proteins.It is thought that BRCA1-A complex subunit Abraxas acts as a central scaffold protein responsible for assembling the various components of the BRCA1-A complex, and mediates recruitment of BRCA1 [, ]. Similarly, Abro1 probably acts as a scaffold facilitating assembly of the various components of BRISC [] - the protein does not interact with BRCA1, but binds polyubiquitin []. The primary sequences of these proteins contain an MPN-like domain [].This entry represents the plant members of FAM175. | Short Name: | FAM175_plant |
