Protein Domain : IPR009089

Type:  Domain Name:  DNA double-strand break repair and VJ recombination XRCC4, N-terminal
Description:  XRCC4 is essential for non-homologous DNA end joining (NHDJ) in eukaryotes, which is required for double-strand break repair, and V(D)J recombination in immunoglobulin and T-cell receptor genes. XRCC4 forms a complex with DNA ligase IV, and acts as a regulatory element required for the stability and activity of the ligase. XRCC4 forms an elongated dumb-bell-like tetramer consisting of a C-terminal stalk that interacts with DNA ligase IV and an N-terminal globular head. The N-terminal head domain consists of a beta sandwich and a helix-turn-helix (HTH) motif, which may be involved in DNA binding [, ]. Short Name:  XRCC4_N
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0 Child Features

0 Contains

2 Cross Referencess

Identifier
G3DSA:2.170.210.10
SSF50809

1 Found In

DB identifier Type Name
IPR010585 Family DNA repair protein XRCC4

4 GO Annotations

GO Term Gene Name
GO:0003677 IPR009089
GO:0006302 IPR009089
GO:0006310 IPR009089
GO:0005634 IPR009089

4 Ontology Annotations

GO Term Gene Name
GO:0003677 IPR009089
GO:0006302 IPR009089
GO:0006310 IPR009089
GO:0005634 IPR009089

0 Parent Features

748 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
evm.model.supercontig_58.53 PAC:16423026 Carica papaya 224  
29844.m003159 B9RTD9 PAC:16810867 Ricinus communis 265  
Cucsa.186130.1 PAC:16967778 Cucumis sativus 616  
Cucsa.218100.1 PAC:16969631 Cucumis sativus 233  
orange1.1g047048m A0A067DWF0 PAC:18108859 Citrus sinensis 240  
AT3G23100.2 Q682V0 PAC:19659415 Arabidopsis thaliana 264  
AT3G23100.1 Q682V0 PAC:19659414 Arabidopsis thaliana 264  
Thhalv10022194m V4M5J7 PAC:20183456 Eutrema salsugineum 235  
Thhalv10010774m V4NGB7 PAC:20207213 Eutrema salsugineum 165  
Thhalv10010992m V4L4C1 PAC:20207802 Eutrema salsugineum 135  
Thhalv10008817m V4KQJ2 PAC:20188235 Eutrema salsugineum 198  
Ciclev10005689m V4RZR5 PAC:20791586 Citrus clementina 256  
Ciclev10007171m V4RZS0 PAC:20791801 Citrus clementina 243  
Ciclev10005690m V4RZR0 PAC:20792097 Citrus clementina 256  
Potri.010G075900.1 A0A2K1YQH5 PAC:26978571 Populus trichocarpa 255  
Potri.004G052200.1 B9H2M6 PAC:26991908 Populus trichocarpa 244  
Gorai.011G171700.1 A0A0D2VNB2 PAC:26812319 Gossypium raimondii 261  
66467 C1N8R0 PAC:27344707 Micromonas pusilla CCMP1545 508  
54905 C1NAH2 PAC:27343679 Micromonas pusilla CCMP1545 357  
185950 C1MSI6 PAC:27341922 Micromonas pusilla CCMP1545 545  
Thecc1EG018355t1 A0A061EG53 PAC:27455036 Theobroma cacao 478  
Thecc1EG018355t2 A0A061EFE6 PAC:27455037 Theobroma cacao 339  
Thecc1EG020798t1 A0A061ELJ5 PAC:27453448 Theobroma cacao 263  
Thecc1EG020798t3 A0A061ENI1 PAC:27453446 Theobroma cacao 277  
Thecc1EG020798t2 A0A061EM56 PAC:27453447 Theobroma cacao 276  
Migut.G00439.1.p A0A022R2F0 PAC:28943918 Mimulus guttatus 259  
Araha.5814s0002.1.p PAC:28844642 Arabidopsis halleri 264  
Glyma.10G184800.1.p I1LC95 PAC:30478120 Glycine max 256  
Glyma.10G184800.2.p K7LK73 PAC:30478121 Glycine max 181  
Glyma.02G012800.1.p K7K5W8 PAC:30509422 Glycine max 764  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11702069
            11080143