3 Ontology Annotations
GO Term | Gene Name |
---|---|
GO:0030071 | IPR016901 |
GO:0031145 | IPR016901 |
GO:0005680 | IPR016901 |
Type: | Family | Name: | Anaphase-promoting complex, subunit 10 |
Description: | The anaphase-promoting complex (APC) or cyclosome is a multi-subunit E3 protein ubiquitin ligase that regulates important events in mitosis, such as the initiation of anaphase and exit from telophase. The APC, in conjunction with other enzymes, assembles multi-ubiquitin chains on a variety of regulatory proteins, thereby targeting them for proteolysis by the 26S proteasome.One of the subunits of the APC that is required for its ubiquitination activity is Doc1/Apc10, a protein composed of a Doc1 homology domain that has been identified in a number of diverse putative E3 ubiquitin ligases []. The Doc1 homology domain forms a beta-sandwich structure that is related in architecture to the galactose-binding domain of galactose oxidase, the coagulation factor C2 domain and a domain of XRCC1. This group represents a subgroup of subunit 10. | Short Name: | APC_su10 |
GO Term | Gene Name |
---|---|
GO:0030071 | IPR016901 |
GO:0031145 | IPR016901 |
GO:0005680 | IPR016901 |