Type: | Repeat | Name: | TSP type-3 repeat |
Description: | This entry represents the calcium-binding type 3 (T3) repeats found in extracellular calcium-binding multifunctional proteins, thrombospondins (TSPs). The T3 repeats lack secondary structure and are organised around a core of calcium ions; two DxDxDGxxDxxD motifs per repeat each encapsulate two calcium ions in a novel arrangement []. TSP type-3 repeat can be found in the following proteins: Cartilage oligomeric matrix protein: may play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin [].Outer membrane porin F from bacteria []. Alpha-agarase: hydrolyses agarose, agarohexaose, neoagarohexaose and porphyran [, ]. | Short Name: | TSP_type-3_rpt |