Type: | Domain | Name: | Sirtuin family, catalytic core small domain |
Description: | The catalytic core of sirtuin proteins consists of a large and a small domains. The large domain has a Rossmann fold and binds NAD+. The small domain is composed of residues from two insertions in the Rossmann fold that form a helical and a zinc binding modules [, ]. This entry represents the catalytic core small domain. | Short Name: | Sirtuin_cat_small_dom |