Protein Domain : IPR006338

Type:  Family Name:  Thioredoxin/glutathione reductase selenoprotein
Description:  This entry represents thioredoxin reductase family, including thioredoxin reductase 1 and 2 from animals. This homodimeric, FAD-containing member of the pyridine nucleotide disulphide oxidoreductase family contains a C-terminal motif Cys-SeCys-Gly, where SeCys is selenocysteine encoded by TGA (in some sequence reports interpreted as a stop codon). In some members of this subfamily, Cys-SeCys-Gly is replaced by Cys-Cys-Gly. The reach of the selenium atom at the C-terminal arm of the protein is proposed to allow broad substrate specificity [, ]. Short Name:  Thioredoxin/glutathione_Rdtase
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0 Child Features

2 Contains

DB identifier Type Name
IPR004099 Domain Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IPR012999 Active_site Pyridine nucleotide-disulphide oxidoreductase, class I, active site

2 Cross Referencess

Identifier
PTHR22912:SF23
TIGR01438

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0004791 IPR006338

1 Ontology Annotations

GO Term Gene Name
GO:0004791 IPR006338

0 Parent Features

5 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
70201 C1MLK3 PAC:27343247 Micromonas pusilla CCMP1545 497  
113706 C1FDI0 PAC:27398747 Micromonas sp RCC299 402  
29046 A4RRK1 PAC:27417894 Ostreococcus lucimarinus 503  
Cre08.g368400.t1.2 A0A2K3DH08 PAC:30773467 Chlamydomonas reinhardtii 503  
Vocar.0020s0082.1.p PAC:32886782 Volvox carteri 509  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11259642
            8650234