Protein Domain : IPR016580

Type:  Family Name:  Cell cycle checkpoint, Hus1
Description:  Hus1 is a component of the 9-1-1 cell-cycle checkpoint response complex (which consists of Rad9, Hus1, Rad1) that plays a major role in DNA repair. In humans, The 9-1-1 complex is recruited to DNA lesions upon damage by the RAD17-replication factor C (RFC) clamp loader complex. It activates checkpoint response and acts as a sliding clamp platform on DNA for several proteins involved in DNA repair. The 9-1-1 complex is necessary for the recruitment of C12orf32/RHINO to sites of double-stranded breaks (DSB) occurring during the S phase []. Short Name:  Cell_cycle_HUS1
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0 Child Features

0 Contains

1 Cross References

Identifier
PIRSF011312

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0000077 IPR016580
GO:0006281 IPR016580
GO:0005730 IPR016580
GO:0030896 IPR016580

4 Ontology Annotations

GO Term Gene Name
GO:0000077 IPR016580
GO:0006281 IPR016580
GO:0005730 IPR016580
GO:0030896 IPR016580

1 Parent Features

DB identifier Type Name
IPR007150 Family Checkpoint protein Hus1/Mec3

229 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
AUR62002633-RA PAC:36289470 Chenopodium quinoa 271  
AUR62030047-RA PAC:36291746 Chenopodium quinoa 296  
Phvul.004G032600.1.p V7BZF9 PAC:37162979 Phaseolus vulgaris 318  
Zm00008a038279_P01 B4FY76 PAC:37186817 Zea mays PH207 329  
Potri.001G201700.2.p U5GUQ1 PAC:37276251 Populus trichocarpa 318  
Potri.001G201700.1.p U5GUQ1 PAC:37276250 Populus trichocarpa 318  
Podel.01G213900.3.p PAC:37312276 Populus deltoides WV94 318  
Podel.01G213900.2.p PAC:37312275 Populus deltoides WV94 318  
Podel.01G213900.1.p PAC:37312274 Populus deltoides WV94 318  
Bol026762 PAC:37365677 Brassica oleracea capitata 319  
AT1G52530.2 Q709F6 PAC:37394926 Arabidopsis thaliana 319  
AT1G52530.1 Q709F6 PAC:37394927 Arabidopsis thaliana 319  
Anaoc.0007s0866.1.p PAC:37508968 Anacardium occidentale 318  
Pavir.7KG257600.3.p PAC:37686393 Panicum virgatum 329  
Pavir.7KG257600.2.p PAC:37686392 Panicum virgatum 329  
Pavir.7KG257600.1.p PAC:37686391 Panicum virgatum 329  
Pavir.7NG336000.2.p PAC:37622251 Panicum virgatum 329  
Oeu027841.1 PAC:37710369 Olea europaea 324  
evm.model.Scaffold_352.548 PAC:37868130 Coffea arabica 323  
evm.model.Scaffold_633.155 PAC:37897092 Coffea arabica 323  
Sobic.006G155800.1.p C5YCJ4 PAC:37948201 Sorghum bicolor 329  
Pum3090s0001.1.p A0A1X6NI32 PAC:38010956 Porphyra umbilicalis 281  
VIT_209s0002g07360.1 A5C992 PAC:38071115 Vitis vinifera 323  
Gohir.A06G107700.1.p PAC:38126895 Gossypium hirsutum 319  
Gohir.A06G107700.2.p PAC:38126896 Gossypium hirsutum 319  
Gohir.D06G120300.1.p PAC:38103277 Gossypium hirsutum 319  
AH013079-RA PAC:38174157 Amaranthus hypochondriacus 297  
BdiBd21-3.5G0213000.1.p PAC:38221223 Brachypodium distachyon Bd21-3 325  
Cz05g09140.t1 PAC:38242498 Chromochloris zofingiensis 319  
HORVU2Hr1G090950.7 PAC:38371991 Hordeum vulgare 293  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            21659603