Protein Domain : IPR011071

Type:  Domain Name:  Polysaccharide lyase family 8-like, C-terminal
Description:  Proteins containing this C-terminal domain consist of a group of secreted bacterial lyase enzymes capable of acting on a variety of substrates. One such enzyme is hyaluronate lyase, a Streptococcal surface enzyme that degrades hyaluronan and chondroitin, thereby helping to spread the bacteria throughout host tissues []. Hyaluronate lyase () is a four-domain enzyme containing an N-terminal carbohydrate-binding domain, a spacer domain, a catalytic domain, and a C-terminal domain that modulates access to the catalytic cleft of the enzyme. The C-terminal domain has a beta sandwich fold consisting of 10 strands in two sheets. Other bacterial enzymes that display this structure include the C-terminal domain of chondroitin AC lyase () [], the C-terminal domain of chondroitin ABC lyase () [], and the C-terminal domain of xanthan lyase () []. This entry represents the C-terminal domain of hyaluronate lyase, chondroitin AC lyase, chondroitin ABC lyase and xanthan lyase. Short Name:  Lyase_8-like_C
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1 Child Features

DB identifier Type Name
IPR004103 Domain Polysaccharide lyase family 8, C-terminal

0 Contains

1 Cross References

Identifier
SSF49863

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0005975 IPR011071

1 Ontology Annotations

GO Term Gene Name
GO:0005975 IPR011071

0 Parent Features

5 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
57697 C1E3I8 PAC:27400495 Micromonas sp RCC299 1539  
Brara.I02701.1.p A0A397Y577 PAC:30640944 Brassica rapa FPsc 260  
Sphfalx0200s0002.1.p PAC:32601224 Sphagnum fallax 155  
Aqcoe1G445800.1.p A0A2G5CAG0 PAC:33077632 Aquilegia coerulea 171  
Eruve.0774s0002.1.p PAC:39900773 Eruca vesicaria 728  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            14523022
            10329169
            12706721
            12475987