1 Proteins
| DB identifier | UniProt Accession | Secondary Identifier | Organism Name | Length |
|---|---|---|---|---|
| 61800 | C1FI96 | PAC:27397764 | Micromonas sp RCC299 |
462
 |
| Type: | Domain | Name: | Reeler domain |
| Description: | The reelin domain is a ~170 amino acid module, which has been identified in the amino terminus of the extracellular matrix proteins reelin and F-spondin(renamed Spon1). The spondin domain is found in association with other modules, such as the thrombospondin type I repeat (TSP1),the spondin domain, the fibronectin type III domain or the Kunitz trypsin protease inhibitor domain. The function of the reelin domain is not yet known [, ].Extracellular matrix (ECM) proteins play an important role in early cortical development, specifically in the formation of neural connections and in controlling the cyto-architecture of the central nervous system. The product of the reeler gene in mouse is reelin,a large extracellular protein secreted by pioneer neurons that coordinates cell positioning during neurodevelopment []. F-spondin and mindin are a family of matrix-attached adhesion molecules that share structural similarities and overlapping domains of expression. Both F-spondin and mindin promote adhesion and outgrowth of hippocampal embryonic neurons and bind to a putative receptor(s) expressed on both hippocampal and sensory neurons []. | Short Name: | Reeler_dom |
| DB identifier | UniProt Accession | Secondary Identifier | Organism Name | Length |
|---|---|---|---|---|
| 61800 | C1FI96 | PAC:27397764 | Micromonas sp RCC299 |
462
|
