Protein Domain : IPR001257

Type:  Domain Name:  Parvovirus non-structural protein 1, helicase domain
Description:  Parvoviruses are some of the smallest viruses containing linear, non-segmented single-stranded DNA genomes, with an average genome size of 5000 nucleotides. Parvoviruses have been described that infect a wide range of invertebrates and vertebrates and are well known for causing enteric disease in mammals. Genomes contains two large ORFs: NS1 and VP1; other ORFs are found in some sub-types and different gene products can arise from splice variants and the use of different start codons []. This entry represents the helicase domain of the Parvovirus NS1 protein; which is required for viral DNA replication []. This domain contains the ATP/GTP-binding site motif A (P-loop). Parvoviral NS1 also regulates host gene expression through histone acetylation []. Short Name:  Parvovirus_NS1_helicase
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0 Child Features

0 Contains

1 Cross References

Identifier
PF01057

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0019079 IPR001257

1 Ontology Annotations

GO Term Gene Name
GO:0019079 IPR001257

1 Parent Features

DB identifier Type Name
IPR014015 Domain Helicase, superfamily 3, DNA virus

3 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Bol040236 PAC:37343887 Brassica oleracea capitata 832  
HanXRQChr14g0443571 A0A251SI46 PAC:40321611 Helianthus annuus 1121  
Pl09G0000142200.1.v1 PAC:44403768 Phaseolus lunatus 489  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            8372437
            15994782
            20097398