Protein Domain : IPR030674

Type:  Family Name:  Nudix hydrolase, AtNUDT22 type
Description:  This entry represents nudix hydrolases, AtNUDT22 and AtNUDT15, from Arabidopsis.The Nudix superfamily is widespread among eucaryotes, bacteria, archaea and viruses and consists mainly of pyrophosphohydrolases that act upon substrates of general structure NUcleoside DIphosphate linked to another moiety, X (NDP-X) to yield NMP plus P-X. Such substrates include (d)NTPs (both canonical and oxidised derivatives), nucleotide sugars and alcohols, dinucleoside polyphosphates (NpnN), dinucleotide coenzymes and capped RNAs. However, phosphohydrolase activity, including activity towards NDPs themselves, and non-nucleotide substrates such as diphosphoinositol polyphosphates (DIPs), 5-phosphoribosyl 1-pyrophosphate (PRPP), thiamine pyrophosphate (TPP) and dihydroneopterin triphosphate (DHNTP) have also been described. Some superfamily members, such as Escherichia coli mutT, have the ability to degrade potentially mutagenic, oxidised nucleotides while others control the levels of metabolic intermediates and signalling compounds. In procaryotes and simple eucaryotes, the number of Nudix genes varies from 0 to over 30, reflecting the metabolic complexity and adaptability of the organism. Nudix hydrolases are typically small proteins, larger ones having additional domains with interactive or other catalytic functions []. Short Name:  Nudix_hydrolase_AtNUDT22
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0 Child Features

0 Contains

1 Cross References

Identifier
PIRSF038132

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0016787 IPR030674

1 Ontology Annotations

GO Term Gene Name
GO:0016787 IPR030674

0 Parent Features

9 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
AT1G28960.5 Q8GYB1 PAC:37395256 Arabidopsis thaliana 293  
AT1G28960.6 Q8GYB1 PAC:37395259 Arabidopsis thaliana 285  
AT1G28960.3 Q8GYB1 PAC:37395258 Arabidopsis thaliana 293  
AT1G28960.1 Q8GYB1 PAC:37395257 Arabidopsis thaliana 293  
AT1G28960.7 Q8GYB1 PAC:37395260 Arabidopsis thaliana 285  
AT2G33980.3 A0A1P8B2A3 PAC:37381593 Arabidopsis thaliana 319  
AT2G33980.2 Q0WN57 PAC:37381595 Arabidopsis thaliana 259  
AT2G33980.4 Q0WN57 PAC:37381596 Arabidopsis thaliana 259  
AT2G33980.1 O22951 PAC:37381594 Arabidopsis thaliana 302  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            16378245