Protein Domain : IPR003342

Type:  Domain Name:  Glycosyl transferase family 39/83
Description:  The biosynthesis of disaccharides, oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes catalyse the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. A classification of glycosyltransferases using nucleotide diphospho-sugar, nucleotide monophospho-sugar and sugar phosphates () and related proteins into distinct sequence based families has been described []. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. The same three-dimensional fold is expected to occur within each of the families. Because 3-D structures are better conserved than sequences, several of the families defined on the basis of sequence similarities may have similar 3-D structures and therefore form 'clans'.Dolichyl-phosphate-mannose-protein mannosyltransferase proteins belong to the glycosyltransferase family 39 () and are responsible for O-linked glycosylation of proteins. They catalyse the reaction: Dolichyl phosphate D-mannose + protein ->dolichyl phosphate + O-D-mannosyl-protein.The transfer of mannose to seryl and threonyl residues of secretory proteins is catalyzed by a family of protein mannosyltransferases in Saccharomyces cerevisiaecoded for by seven genes (PMT1-7). Protein O-glycosylation is essential for cell wall rigidity and cell integrity and this protein modification is vital for S. cerevisiae [].Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase proteins belong to the glycosyltransferase family 83 (). They catalyse the reaction: 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid IV(A) = lipid II(A) + di-trans,octa-cis-undecaprenyl phosphate. Short Name:  Glyco_trans_39/83
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0 Child Features

0 Contains

1 Cross References

Identifier
PF02366

1 Found In

DB identifier Type Name
IPR016950 Family Mannosyltransferase, MA4085, predicted

3 GO Annotations

GO Term Gene Name
GO:0000030 IPR003342
GO:0006493 IPR003342
GO:0016020 IPR003342

3 Ontology Annotations

GO Term Gene Name
GO:0000030 IPR003342
GO:0006493 IPR003342
GO:0016020 IPR003342

0 Parent Features

5 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Pum0103s0048.1.p A0A1X6PD91 PAC:38008939 Porphyra umbilicalis 518  
Pum0014s0111.1.p A0A1X6PL76 PAC:38015809 Porphyra umbilicalis 598  
Pum0134s0022.1.p A0A1X6PA86 PAC:38011970 Porphyra umbilicalis 564  
Pum0256s0042.1.p A0A1X6P2J7 PAC:38010691 Porphyra umbilicalis 410  
Pum0093s0047.1.p A0A1X6PDS6 PAC:38011653 Porphyra umbilicalis 599  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9334165
            8918452