Protein Domain : IPR006777

Type:  Family Name:  Minor spike protein
Description:  This entry represents the minor spike protein (also known as H protein), which is a minor spike component of the viral shell. It is involved in the ejection of the phage DNA in the host and is injected with the DNA in the periplasmic space of the host. It is involved in the determination of the phage host-range [, ]. Bacteriophage PhiX174 is one of the simplest viruses, having a single-stranded, closed circular DNA of 5386 nucleotide bases and four capsid proteins, J, F, G and H. A single molecule of H protein is found on each of the 12 spikes on the microvirus shell of the bacteriophage. H is involved in the ejection of the phage DNA, and at least one copy is injected into the hosts periplasmic space along with the ssDNA viral genome []. Part of H is thought to lie outside the shell, where it recognises lipopolysaccharide from virus-sensitive bacterial strains []. Part of H may lie within the capsid, since mutations in H can influence the DNA ejection mechanism by affecting the DNA-protein interactions []. H may span the capsid through the hydrophilic channels formed by G proteins []. Short Name:  Microvir_H

0 Child Features

0 Contains

3 Cross Referencess

Identifier
PF04687
PIRSF004160
PD014178

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0046718 IPR006777
GO:0019028 IPR006777

2 Ontology Annotations

GO Term Gene Name
GO:0046718 IPR006777
GO:0019028 IPR006777

0 Parent Features

2 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
HORVU3Hr1G056930.1 PAC:38387646 Hordeum vulgare 46  
HORVU0Hr1G006260.1 PAC:38337615 Hordeum vulgare 149  

5 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10739948
            8158636
            10225278
            8433365
            16143459