Protein Domain : IPR011114

Type:  Domain Name:  DNA helicase, Holliday junction RuvA type, domain III, C-terminal
Description:  In prokaryotes, RuvA, RuvB, and RuvC process the universal DNA intermediate of homologous recombination, termed Holliday junction. The tetrameric DNA helicase RuvA specifically binds to the Holliday junction and facilitates the isomerization of the junction from the stacked folded configuration to the square-planar structure []. In the RuvA tetramer, each subunit consists of three domains, I, II and III, where I and II form the major core that is responsible for Holliday junction binding and base pair rearrangements of Holliday junction executed at the crossover point, whereas domain III regulates branch migration through direct contact with RuvB.The domain represents the C-terminal domain III of RuvA. This domain plays a significant role in the ATP-dependent branch migration of the hetero-duplex through direct contact with RuvB []. Within the Holliday junction, this domain makes no interaction with the DNA. Short Name:  DNA_helicas_Holl-junc_RuvA_C
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0 Child Features

0 Contains

2 Cross Referencess

Identifier
PF07499
SSF46929

1 Found In

DB identifier Type Name
IPR000085 Family Bacterial DNA recombination protein RuvA

5 GO Annotations

GO Term Gene Name
GO:0005524 IPR011114
GO:0009378 IPR011114
GO:0006281 IPR011114
GO:0006310 IPR011114
GO:0009379 IPR011114

5 Ontology Annotations

GO Term Gene Name
GO:0005524 IPR011114
GO:0009378 IPR011114
GO:0006281 IPR011114
GO:0006310 IPR011114
GO:0009379 IPR011114

0 Parent Features

7 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Migut.F00696.1.p PAC:28933652 Mimulus guttatus 219  
Medtr1g111700.1 A0A072VR72 PAC:31094661 Medicago truncatula 76  
Pp3s356_30V3.1.p PAC:32937655 Physcomitrium patens 673  
Oropetium_20150105_24941A PAC:36014075 Oropetium thomaeum 76  
HORVU2Hr1G127700.2 PAC:38365211 Hordeum vulgare 66  
Isati.1036s0023.1.p PAC:39317542 Isatis tinctoria 94  
Zosma07g00940 PAC:50102077 Zostera marina 777  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12408833
            10890893