>Brdisv1Kah-51015013m.g 0.5kb downstream atgactggccggcataattgtagcagcggccgtcgccacctccgtgctaatctgggttca gtggactccgaatgctcccctcccaagtcttccggttcctcctactatgatcgcgccgcc gagtgcaaaacccctctcccgaatcggcagcagcaggtcaccgagaagaagcctgatctg ccgaggacgacaccagatgcttcggccaggcgtccgtttctgctcaatctcatccgataa gaagatgaccaggatgacgaagatgaaaccgagaaagatttctccatattttgcaggata tgtgtctgacggcttagcaaggaagaccgagggaggccgcagcagtgcacaaggaagact ctcgtgctgctgaatgtcttgcagttctaagtttctcacagtcagaggtttagaacaggt gtcaaaactttggttgcagataacatcaaacgtgcacattctgggagtactgttttgcaa tagcgttgatccaaataggtcgctaacctgaaggagggttagaggaattcactgtttaga ttagatacaatagtttctaactttttttttccgaaagataaagcttaaagtgctggcttt catacattaagcatgtagaaaagtgtacaagaatgccgcaaggcgaagcaaaggagaaat gaaaaaaaaagagaaacagaaaagaaaggaagaaataaatcatggtggctcccaaagcag tttccttagagctttagcgccagcaaaggcccaatcttgagccgcgtctctgatgaagac caggaactgcctgcctgggacttctttgtcatggaagaccccgttatttcgctcatgcca aatggtccagcaggtgagaatgaagagcgagttgactcccttcttgtgggcgtcggtgga gagagcaagaatgcagccaaggaagtcggtgagggatctgtggtccgcccgaagagcgcc cgcaatgccgttgcagtttatccaggttgccagatcgcaccaaatttgatgggagaaggg gcattcgacgaagaggtgaagcgaggtttccaaattccgtcggcaaagggggaaaagtaa caatttggccatccgcggcgctggagatgatccgcacaccatagccggtcctgcaagagg agcaacgcaaagaatttctgcttgggtggagcccactgctgccaaacgaagttggggaga tcagatttcgagcggcctatgaagtggagcaggtacgcggatttggtggagtagacgccg tcggtggagggggtccagcggatcgagtccggcgtctccgtgagcagcggaggggcctgt cctaagaggcgcctggcggagaggaattcagacacaaactgaatggtgttgtcacggcgc agaatagtttctaacttcagaaaactgtttcacgtctcaacgtaccattgttgtcgcttg ccttgcaagcaaagttcaggtccttgctaattgaaaacgatacctgcgtttttgaacgaa caggaaaaaaaaagtactgtactgtacgtgtgttgaccataagcttcaagttgttcgaac gttgcactgtcggatgaactagctgcaaacctttcaaaagaaaattgtgaactactgtac catgacatgtctgaaacatggtaggctaacgctaacaattgtgatagtgactgactgaag acctacagagtactagcagggagcccatgcgttgcgacggaatacatatgttcgtcatgt ccaacggagtaaggaaaacgagaactgataacgaaatcttgaagaacaccgacaaacaaa acgagagctcaagaatagaaacatgatttatacagtgtacataaaaaaaaacatgttact tttaagtgtctctcaatataatgctacagctcagaccataattcatgtaactaaaatgtc actctcccttttctgctaagcagctaaaggccgaaatagtgcttaacattgatggcaata atgcttttggagttcatacaacactggaatttggacctgcgaactgagatgtttaggtca caacccaaattacaaatatatgtcgataaactattgttttatttccctgagaggctcgtg gcgtaaccgttggcagttggaatccatgacgtacatgttgaccatgtacaacaaggtgtt aggaggttgagcacaagggagatgaaatggtgcttgtcctcttaaatctgatgctgttct gaacctgcggtgtcccttcgtgccattaggcgtgcttgtcctcggaaaaactaaagcctc cttcacagcctgcctatgcttcttctcctgtgaccaatgttaaaaatagttaatcgatgg cacacgtaaaataaatattaccctataggtttagaattaccagccaaataaaaaattaag ccttaaaagcatgaactcataaaaaaacaagggaatgactgtcaaaatgttgtactcccc ccgatccatattaattatcgaaatattacatgtatctagacgctttttaggcatacatac atccatatttgagcaatgtgagacaattaatatggatgggaggaagtattagtttgtagg ttaactcaaagaaaatagggaataatttagaactgagaaccagagctttattttccattg tgaccatttataattgtgctttccacctcagtgttacttttaagatctgacttactttta aattcatcattttttcttcatattctacttttcagaacatttggaataatttttccattt attcaacgttcttgtatggagtgccactctggaatatttaaagaaacaattggcatgact ggtccttggttgattgagtgcacagtattnatcttaaaactatatctttgttccttttcc cccattcttttaataatttcttacttcctttcactgggaaattcatacttaaatatgtat ctaaaaataacaggagtatatcatctgtatagacatcaggtttataggttataatatcat aagaaatgaatttagatattgaaacttcatcaagtttacccgccttgtaaggcttataaa gaatattatcgtatatgaatcaattgatgattctaattggcggtcccatatcctgaaata tttatttatataaatgaggatatatatttgagcggatacacagaacaccctgcaaactca ccgcaagggtcgtcgccatttgcaatccatctgggaagaggtgacgatctaactaactgc atgcaacaattaaaggaaaagcgagtcttagcaacgaaaaaattgctttgtgacatgggt taggtaaccaccaccgagaaatatgcgatagacaaatgcccagtttcaccttcaactaaa ggatgggtagatatgaataggcgacatgctgactttgagctccttgtttccggatcagaa gcattacagtcattagtaacattatagatttcttttcaaagaaaagtaatggaatggcga gcctcttgtcgtcactgcaaccctagcatcatgagcaacatcttctcgccacggtggatt catggctccgcccagttctcattttgctctccctctccttgccgagctatgacatgaagc aacaccatcataacagtaatctagtaccaatgaaaaacagaatcagagcccaaagatggt accaaaatgtttagcaaatatgagccggagcctttcctaaccgagagcaatggagaagtc attaccttgtagatgaaagcacgtaagaaaataaaaggtgcgaacaacatgatggaactt cacatggcagcagcaatgtcaggaagaagaaaatggatgcaggaacagcaagaacaggga gcgacatgttgtttctgtgtgcagagaacgctagattcactatctccaccgtgtctttct tcctcccttcccggcgtgcactcaagaaagaggaattcgccacacttgcacaagtctagg aagaaaaatggacataataaatctaagcaaataaaaagcttaggtatcagaacaatgtaa ggaaaataaatagaaataggcatttccatcctacataagatgcatgttttcgatatcttg agaagatctggaaatgcttaataaatatttcattcaaacaagttccaggatacatgaatg ttttagttcatcaatggagactagagaattgtgagcagcaacaccactatatccctctgt ttctttttataagcccttttggcaagtcatttgccaaaacgtcttataaaagggaacaga gggagtagtttccagatcctccaaagatgaacattaatttagtgtagcagcatcaaatct aaagctatagtccttaaatggagatacaaaaacacgcttaaacttgcatcaataagacaa tgctagaacaaataggaataaatataggttcagctagttactatggggatggagtcccta aatggagcaacaaatcctgtacgcaagaaataagctattgctcctttgtgcctgacagaa aaaaaaaacatccgaagctccagaagcaaccatatcatatctatgagaaaaatatacagc aaatcaataagttttactcgtatgaattaaccaaattatggcaaatttgcttcttaataa tttggtttcttggacacagctaaccatctccatcagaaaccaatgaacacaataaatcta ttcatcttacctgtcatcttgtagatccgatgggtgattgcagagagtttggcggccggc ggccccgcacacccgtcattgaggtgactcctccggccggatcgggctctccgccaccgc cggcgggcgaaggcgggcggttggcgggtggagcgacggccgggcgaagcgcgacggtgg gcggttgacgggcggaactacgggccacggcggagacgagtggagcgcgacggcggccgc gggctggcgaagtgtggagacgggcgatgcgacggcggcggagggctgtgggcgggcgac gggtagcgtcaggtgcgatagctctttcttgatcggagacgccggcggcagggaaggatc gcggtggctgggggacatggcgttttttcacctgggggtatgatgggtcgcggcggcgga tctggcgtgcgtgatcgattggcagatgtaggccatggcggaatttccacctggtaatgg atatacgcggtggaaaaagaagcaaacgtggcccactagggcaagttcggttgcaacatt ccccgcaggattgagagggatcatgaaaaaaatgcactaaaatgacagcgatccatgtca atcccggtggggatgggcataaccgaactagtccttaccgggtacaaaaccaacgctgta cgacagaccggttgacccgtgtttttattggcattattttttgttagcgtgtgctagtgt ttttattggcattatttttttagctttagagtccttctttggtgtgccgataaagatttt gtggttcaacgatctgtacttttagggaatcatcaccggcgcaaatacgttcaacggtca tggttttcaattcttcagaggtattcaagttggtgcaggtgttcgagtgacagtgtcgtt gctccagtttgattgcaatatatttaccgaagcattggccgtacttcgtgttgcgaagct taataccatggagaagatttctttgaaatacttcaatgtaatttttagttacagaagttt ctttgtactttatttgatttttatgcaaagcattgtacttctaatggatgtcacatttaa ataaaattacagatgattctaaaaaaaaagaatcgttggctcctctattgtccggtttct tttttctgaaagttagcaggagagccgctaaaattctattaagaaataaagaccgatgac cgtgaccccgtctataaggaaaaacggacataaaaacagtacaaggtggcttatattaga gtaaagccaaaaaaatcttgacaaccagaagtaacctaaacaagctaggcctagaacatc gccaagcgacaagccacaccagccagatcaaattttagtctaaagtgttgggttttggct tatagccaagccaaatttaggttgaagagaggtattttataataatcatgtcaattgtta aaactgtgagattgacacgtggacaaagcataggtgtcatggatcttgatttgtggattt gactatagggaatgcaatgctttgagcgaatttaaaggagcattcacaatttatcaagta ttttgattttgaaactgatagtccaaataagcaacacatttaatacctctaaggatcagc agctgctcattctcattaagaacggtttggaagcagaaaatttatactccccctctgact caaattacttgtctcaaaatttgtctaaatatgaatgtatctatgtttaaaaaatgcata gatacatgtaatatttcgacgagtaatatggatcggatatcatgaagaaatatcacatga attaatttaacttttataaaaacataaaaacagatattttccagcgttccaacacatgcc ccaaatagcccccactgcctctccccggtgcgggtggtgccagatcgatcaaaacgaaag ccaaatcgaaatcccaattgcatcttccgcctctccgttcgtatggctggccggcgtaga cgacactgcggccgtcgggctaaggtagcggcgaagcctgccgaagactcgccgcccgac acggacccgacatcctcgtcctcttccccttccgagcgcgccgcctgccagcacaaatcc cctctctgggcttgaactgcaccaggacgacgacaatgggtcttggactcaatcggacaa gagggccatgaggcggaggctgctggacatcatccaccgcttctacctcgacgccatctc gcggctgccccccgccgagttcaggaggaccaccggcctcgcgcggggcctccacgtcgg tggccactgcttcggtccactccaccccgtccacaacatcgtcgtcaactccatctggta cgctgccgccttccccgttgccggcagcgacgacgaagatgaggccaacgcactgctcag caccgacggtatctgccaccgctctctcgacgggctcgtggccgccctccgcgacctgtg cccatccatctccagcggtgatgctctgtggcggctcttctccgctggcgctgacctcac cgctgccgtcgcactggcaaacggggtcagcaaatcaagcgccctgcgtgtcgtcgcgtc tcagggccatgccgcttttcatctggccgccctggttgcgcgacaccccgatcccacagc ctttgctcacttcgcatcatcagcgttaccttctatcaatgggcaacacaacattgttca gctcttgatcatgaaacatgtgctcgcatctcggcacatcaactacctctccaaagtgct ggtgccgtcatcaccacatgaaccttctgtgtcgcttctcatgctaagcgcaccagtcct tgactgcattgcatctcagaagcagcaatttaagggcataggaaaacaagtggttaatgt tgtcaacatggcactgcaacaatacactcaacggtctggtgaacagctgaagcttcattc tgtgtgtggtgctagtctgctaaaggaggagggactagagaactgttaccacatcaattt cctggcgtaccacgagggctctggttcggcagtaggtgccactgtgctcttcttcactga ggcaattattctttcttgtgatgagactgatatccgcctatgtgcgccagttgatccggt cacagacattggtatgcccttcctctgtgaaacagttcaattttgatttgggtgtacatg aatgaaacacaatgttgaatctgtgtgaagcatggctggcaactaccaccatgaacttta tttattttcttttagttacttcttattcaagtttttattgtcaaggagcatttgctgttg gtacaaaagttgatattaccggtcctctttagctgaaatctcaattagccaaggtgcgtc tattttacatatggcagtatcctttctttgtccagagtgttcacagtgaagtgcttcttc ttgcttcaccgaacaaccgagagcttttctggtccaagtattcagtcaccaattagcata ttttccggtgtgttccatatttcaggcttgattagcagctgagttcgatgctctgctgtc aactgattgactcgttccactagtagcttccagtatcatcattttccagctacaaataat tcccttgaatacaatatacacttcccctgtcctcattaaaattatgccacattgcaagct ctcctaaatgttgccttacgatattagtattcccttccttaggcccttcagttttgtgta cctgtagaattgatttgattatgaacttgttgatagttcacatggctacttgattgttta tcagactaatatcatccttcatttaattgctttgacatattcatatcagcaacacgcttt atccttatctatgtgcagatatggttcgatgatactccctctttttcaaattgtaaatcg ttttagctttaggtgtatagtttttcctacaaaccttagatatacgctatttctagatgc atagtaaaatctatctatgtactccctccgtcacatattaaataactcaaatttgtccaa atatggatgtatttataactaaaaaacgtctagataaatacaatatttcatcactaaata tgggacggagggagtatgaaaaaagccaaaatgacttacaatttggtctttcttgtttta gtccatgcctgagaagttgtaaccaaataacagttactgacctttcttgaaaattcttag gctgctgctttgcttgcgagagcaacaggaagaaggttgttcaccccttttatgatgaat accttggtggccgtgaatttcaagaggatgaagtcgactatgacaatgattttccaagtc ccttggatgcggactatatctttttttatgctgatagagacgggggttttgcaaattact tgtcgagggagagcacgggtcattgaggttggttgttaggagtggtgtcgtgctgttaat ctttgaacctggaagacaaaccatagggactggttgggtgtctgtggcagcaactaagca agtgcgattgtacacctactgggttgtttttcaaaatagcatagaatactgcagctaccg cggtgtctgtggcatcatcaatttaatctctctggttatcatgactaggatgattatgca ctatttctccaatcatgtattgtaaacaaacttgctacatttcagagcatgaggttagta gggccatggaaatgttctcttctcttccttgtgatattcgaaagagacattaatggtaca ttcagctactatattgtggcaaaactgaagcattcctctcggtataatagtttttctgac cctatttgtaaatacattcaagggattttatcaatttcatttcttctgcatactcggcta gaaactattgattcaatagacaagcgggaacacgtgtgctgaatagattttctctatttt ctcttcaagcccacccggcggccaccttgcgcaggaggtgttcgacgatttgccaaggcc atggattcagacaacaaggagatgctcgccgtgttgtttgatgaggaagtcgctgctgtc gcactacacgatggaccaaacctaggggcacatttgctgccgacaaagatcactaaagag cgcggcataactgccggcaaagagttactaccgacagtcttgcctaccgcctataacgct gccggcaaaagtctttgccggcagttcaactgccctgctagcagtacttttgccgggcga tcgatgatgcggcctccgatggcgaagaggagcatcaggtgatcctctctgcccttctta tcctggtcgcccaggatgcacaacggccggcatgggaggatcgaggaagggctgccgtaa gagcaaggcgagacagaggatggagggctactgcatgttgtacgctgaatattttgccga tgatccattgcacaacgatgtggtctttcggcgccgtttcaggatgtctcggaagctttt tttgaagattgccgagtacctcagggagtaagacgtttacttcaaattgaagagaggcgt ggtcggcacacttggtttctcaacaattcagaaatgcacgttatccctccggttgcttgg gtatgaaattcctgccgatacacaagacgattacctccgcatggtcgagtccacacccat cgattgcatgtacaggttcagtaaggcaatggtggcagtgttttgagatatctacttgag aacacccactgcagaagacacaactcagatcttgcacagaacgcagaaagagaattccta ggcatgcttggcagcatcgactgtatgcattggttatggaagaactgaccatttgcacac caaggcatgtataaaggtcacaaaggatcatgtagtgtggtgcttgaggcagtggccgat caggatctgtggatttggcatgttttctttggtatggcaggatcgcacaatgacatcaat gtgctacaatggttgaatgtgttcgccaagcttgttcaagacactcctcctccgatgaac tatgagatcaatggccatatgtacactgtcgaggttggttctcggcaatgccaattgtta tggacttgtgattcgagagaagaagtgtgtgttggcgatttttgtcgctaacaaggagaa ggggcacgatttacccaggttcggggccctcatggaggtaatacccctactcctgctcgt ctgtgttggtattgatgatgagattacaagttcgctggaaggctatgttgcgctgattga atctggcgagtgtatatgagatggcttatcctccccacctccccctcctagtcctttata taggtggctaggtctcgggtgcagagtccggatcggttacaacataaaacaaaccctaga aggttttcttatcttgagccgcaatcgaaggtgcttgggcttcacggattgtagtgggcc ttcggtgggctttccgccgagtcatagtaggtatgccaaaggaaaagacttggtaaggta taaccaacctggcagatggcatttacgatctatccaagatggtcaactttcgtgaagatg atctcaaacgcaccactaggaggagcaagatctcggtttgcgacgcaacaggaagcttgt aggaaggttatcaagcgggcatttggtgtgttgcaggctcgatttgctattgtccggtac cctgctcttacttggtccaatgatcagatgtgggaggtcatgactgcctatgtgatcgtg cataaatgataattatgagcgaccggaaatgtccggtgtattgaaccgtatgaacggata gattctttagccgatgttgatcatcatgtgccagccgcctttgctgattttctcggcaag cgtcaggaaattcgagacagcggtactcatcagcagcttcaagatgatctggtggagcat ttgtggaggctcgaaaaaaagttctaatttttcttaatcgtgattcaaaacttatcaaat agagtactcgtttcaatttgcattatttaagaaatttggtataggaaaggggtttgaggg tctgtccacacagaaccggttcaaccccaaactgaaaatcaaggctcgagcgtggatgct ctaactccgtcccgtcccaatccctaccggcggtaaagcgatacaaagagctagggcatg gctagccggcgtaaccgtagccgccgccgccgccgtctccgcgctaaggtagattcggag gcatccgaatcatcgtctccccaatagtcctccgatgaccgcgcttcccagcgcattccg aatcggcagcagcaggtgcttgaggagaggcctgatctgccgaggaggacacgggatgct cgcgatgtgcgggcgttcgtgctgggtgtcatccgcggctactacatcgacgccatcgcc cggctgcccgctaccgagctcaggaccaccctcgcgcgcggtctccttgttggcgggcac tgctacggcccactccaccccgtccacaatattatcctcaattccgtctggtacgccgcc gccttccccttccgcgccgaccccatcgatgttgacgtcgtcaccaccgacgccataaac cgccttgcccgccgctctctcgatggcttggttgcctatctctgcaaccgatcccctgac ctttcccacgacgacgccctctggcacctcgccctctcccatggcgcactcggtgctgtg ccgttcggccgcacgggattggaatcctttccattccaggtggctgcgcaggctgcgcgg cacccaaaaccttccgccctcatgagcttcgtcacctcggtgctgccacctgtggaacgc gatgtgctctcgctgcttgctggcaggcgtaggctctcttcgcatgacatcctgcgcctc tccgccatgctgcagcctctcccgctgccagatgcactggcacagcagccgtgttctcaa gagctgagcataagaatcggccgaatcattgccgagaggncaagagggccatgaggcgga ggctgctggacatcatccaccgcttctacctcgacgccatctcgcggctgccccccgccg agttcaggaggaccanaaaattatgttatcatctacaagttcaaataaatgcactatcaa atcatatttatggagaattcactgaaactaatttgatattgtagatgttggtgcattttt ctataaacttgaccaaagtataatttggaatagacagagtagatgaaatcttcttatgga tcttgcttaatgccagaacaaacaatggttctgcagaaaaagaaccaataataggtttac gctgatttatatgcagcagtgattgccttgtattgtactccaaaggattttgggatctac acggtgtgcattggcatatgtctatttttaatgtagagtattgcaacctagttttttttg tacattctgatagtaccatgtcctgtttgcaatatgatgtttgattgatgttaagttcct tttttcttggcgtatttcagtggcagattctgtctctaatcctttttgtggacaaacgca gataattgttatgcctgtgcgaggatcaagaaaaattgaccatccaaatggtgaggagca cttcggagggcatccgcacaggacagatgaaactgaggatgaccgcgattgcccaaccac cattgacgtggactacaggtttttcgatcctgacagagacattgaccttgtgaagtgcta tgctgataagataaatcgtgctgaagctatttattacaagctgggcttgaaaaacaggag cacaaatgatgaagatgtagccagggaagatatcgaagtttattgccggcgatacgtgtg atgcgtaaactaagattaatggggcaccaccaggagtttccaaactaaattcatgtttat agaaatgataacaacataatttgacattcagtgatgagtattaatcaaagtgtgtataga agtgtgccatgtatgatgtctgcacgtatggtgttatgttcctcatttgtatttaattaa aggttcttatggacctagcattggaacacatgaaaaaaaaaagataattgaaagaaacca tatgcattctagcacaaaacaaatactttgctcgtccatgatacttacatattgatgtca gaatccttttattaattgtgtgtagtaatgtatcatcctgaaataagtttaaataaacaa aaaacatcatctcattgttatgtgtttttttaggacaccccaaagagacagggggctcct gcaatccattatagaagaaatagagttgtccggttaattagagaaaaccaggcgaaaacc agatacaaaggggacgaaacc