Protein Domain : IPR001636

Type:  Family Name:  Phosphoribosylaminoimidazole-succinocarboxamide synthase
Description:  Phosphoribosylaminoimidazole-succinocarboxamide synthase () (SAICAR synthetase) catalyzes the seventh step in the de novopurine biosynthetic pathway; the ATP-dependent conversion of 5'-phosphoribosyl-5-aminoimidazole-4-carboxylic acid and aspartic acid to SAICAR [, ].In bacteria (purC), fungi (ADE1) and plants (Pur7), SAICAR synthetase is a monofunctional protein; in animals it is the N-terminal domain of a bifunctional enzyme that also catalyse phosphoribosylaminoimidazole carboxylase (AIRC) activity (see ).This entry represents the monofunctionl protein. Short Name:  SAICAR_synth
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1 Child Features

DB identifier Type Name
IPR014106 Family Phosphoribosylaminoimidazole-succinocarboxamide synthase, Vibrio-type

2 Contains

DB identifier Type Name
IPR013816 Domain ATP-grasp fold, subdomain 2
IPR018236 Conserved_site SAICAR synthetase, conserved site

1 Cross References

Identifier
TIGR00081

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0004639 IPR001636
GO:0006164 IPR001636

2 Ontology Annotations

GO Term Gene Name
GO:0004639 IPR001636
GO:0006164 IPR001636

0 Parent Features

40 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Araha.7551s0009.1.p PAC:28842442 Arabidopsis halleri 411  
Glyma.14G178900.2.p A0A0R0GF61 PAC:30533195 Glycine max 389  
Glyma.14G178900.1.p I1MAX9 PAC:30533194 Glycine max 410  
Brara.A02789.1.p A0A398AWY3 PAC:30637645 Brassica rapa FPsc 408  
Brara.C03814.1.p A0A398A4E6 PAC:30616446 Brassica rapa FPsc 410  
Bostr.19424s0545.1.p PAC:30661882 Boechera stricta 411  
Cre03.g202113.t1.1 A8JBQ5 PAC:30786901 Chlamydomonas reinhardtii 372  
SapurV1A.0638s0030.1.p PAC:31448353 Salix purpurea 350  
SapurV1A.0638s0030.2.p PAC:31448354 Salix purpurea 350  
SapurV1A.0654s0110.1.p PAC:31424332 Salix purpurea 350  
Spipo4G0013700 PAC:31504564 Spirodela polyrhiza 398  
evm_27.model.AmTr_v1.0_scaffold00135.51 W1P7I0 PAC:31560941 Amborella trichopoda 389  
Eucgr.F00397.1.p A0A059BK46 PAC:32056580 Eucalyptus grandis 370  
Prupe.1G526100.2.p A0A251RHH5 PAC:32118746 Prunus persica 284  
Prupe.1G526100.5.p A0A251RGW3 PAC:32118743 Prunus persica 389  
Prupe.1G526100.4.p A0A251RH40 PAC:32118745 Prunus persica 355  
Prupe.1G526100.3.p A0A251RH03 PAC:32118744 Prunus persica 368  
Prupe.1G526100.1.p A0A251RGR8 PAC:32118742 Prunus persica 402  
GSMUA_Achr7P19070_001 PAC:32302991 Musa acuminata 390  
Manes.02G148000.1.p A0A2C9WED6 PAC:32332968 Manihot esculenta 135  
Manes.18G062300.2.p A0A2C9U121 PAC:32348941 Manihot esculenta 398  
Manes.18G062300.1.p A0A2C9U1R5 PAC:32348940 Manihot esculenta 413  
Pahal.J01877.1 A0A2S3H0H4 PAC:32490257 Panicum hallii 402  
Kalax.0103s0014.1.p PAC:32572634 Kalanchoe laxiflora 384  
Kalax.0044s0101.1.p PAC:32572418 Kalanchoe laxiflora 384  
Kalax.0679s0015.1.p PAC:32577451 Kalanchoe laxiflora 136  
Sphfalx0001s0058.1.p PAC:32605289 Sphagnum fallax 453  
Sphfalx0001s0058.2.p PAC:32605290 Sphagnum fallax 452  
Sevir.2G250300.1.p A0A4U6VXL4 PAC:32638447 Setaria viridis 403  
Seita.2G239700.1.p K3ZTW8 PAC:32718940 Setaria italica 403  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1574589
            15641804