| Type: | Conserved_site | Name: | SAICAR synthetase, conserved site |
| Description: | Phosphoribosylaminoimidazole-succinocarboxamide synthase () (SAICAR synthetase) catalyzes the seventh step in the de novopurine biosynthetic pathway; the ATP-dependent conversion of 5'-phosphoribosyl-5-aminoimidazole-4-carboxylic acid and aspartic acid to SAICAR [, ].In bacteria (purC), fungi (ADE1) and plants (Pur7), SAICAR synthetase is a monofunctional protein; in animals it is the N-terminal domain of a bifunctional enzyme that also catalyse phosphoribosylaminoimidazole carboxylase (AIRC) activity (see ). | Short Name: | SAICAR_synthetase_CS |
