Protein Domain : IPR009015

Type:  Domain Name:  L-fucose isomerase, N-terminal/central domain
Description:  L-fucose isomerase () converts the aldose L-fucose into the corresponding ketose L-fuculose during the first step in fucose metabolism using Mn2+ as a cofactor. The enzyme is a hexamer, forming the largest structurally known ketol isomerase, and has no sequence or structural similarity with other ketol isomerases. L-fucose isomerase is composed of three domains, the N-terminal, central and C-terminal domains. The N-terminal and central domains have a similar topology, consisting of three layers (alpha/beta/alpha) each. The N-terminal domain has a parallel beta-sheet of five strands in the order S2, S1, S3, S4, S5, while the central domain has a parallel beta-sheet of four strands in the order S2, S1, S3, S4 []. Short Name:  Fucose_isomerase_N/cen
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0 Child Features

2 Contains

DB identifier Type Name
IPR012889 Domain L-fucose isomerase, N-terminal-2
IPR012888 Domain L-fucose isomerase, N-terminal-1

1 Cross References

Identifier
SSF53743

1 Found In

DB identifier Type Name
IPR005763 Family L-fucose isomerase

3 GO Annotations

GO Term Gene Name
GO:0016861 IPR009015
GO:0005996 IPR009015
GO:0005737 IPR009015

3 Ontology Annotations

GO Term Gene Name
GO:0016861 IPR009015
GO:0005996 IPR009015
GO:0005737 IPR009015

0 Parent Features

17 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Glyma.15G017200.1.p A0A0R0FV85 PAC:30496914 Glycine max 141  
Glyma.03G027800.1.p A0A0R0KE66 PAC:30518284 Glycine max 360  
Zosma32g00090.1 A0A0K9P864 PAC:33172102 Zostera marina 258  
PGSC0003DMP400009898 PAC:37463409 Solanum tuberosum 81  
evm.model.Scaffold_583.47 PAC:37895851 Coffea arabica 136  
VIT_200s1220g00010.2 PAC:38049691 Vitis vinifera 174  
Carub.0006s3044.1.p PAC:39247199 Capsella rubella 619  
Desop.0209s0179.1.p PAC:39679414 Descurainia sophioides 82  
Distr.0004s0249.1.p PAC:40013656 Diptychocarpus strictus 326  
Glyma.03G027800.2.p PAC:41158997 Glycine max 224  
Glyma.15G017200.3.p PAC:41118177 Glycine max 103  
Glyma.15G017200.2.p PAC:41118176 Glycine max 146  
GlysoPI483463.03G023200.1.p PAC:41185906 Glycine soja 224  
GlymaLee.03G024800.1.p PAC:41252171 Glycine max Lee 224  
Sphfalx01G068000.3.p PAC:41989119 Sphagnum fallax 128  
Phacu.WLD.007G187700.1 PAC:45542577 Phaseolus acutifolius WLD 138  
Distr.0005s24800.1.p PAC:45573056 Diptychocarpus strictus 326  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9367760