Protein Domain : IPR005763

Type:  Family Name:  L-fucose isomerase
Description:  L-fucose isomerase () converts the aldose L-fucose into the corresponding ketose L-fuculose during the first step in fucose metabolism using Mn2+ as a cofactor. The enzyme is a hexamer, forming the largest structurally known ketol isomerase, and has no sequence or structural similarity with other ketol isomerases. L-fucose isomerase is composed of three domains, the N-terminal, central and C-terminal domains. The N-terminal and central domains have a similar topology, consisting of three layers (alpha/beta/alpha) each. The N-terminal domain has a parallel beta-sheet of five strands in the order S2, S1, S3, S4, S5, while the central domain has a parallel beta-sheet of four strands in the order S2, S1, S3, S4 []. Short Name:  Fucose_isomerase
Paste the following link

0 Child Features

4 Contains

DB identifier Type Name
IPR012889 Domain L-fucose isomerase, N-terminal-2
IPR012888 Domain L-fucose isomerase, N-terminal-1
IPR009015 Domain L-fucose isomerase, N-terminal/central domain
IPR004216 Domain L-fucose/L-arabinose isomerase, C-terminal

2 Cross Referencess

Identifier
TIGR01089
MF_01254

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0008736 IPR005763
GO:0030145 IPR005763
GO:0019317 IPR005763
GO:0005737 IPR005763

4 Ontology Annotations

GO Term Gene Name
GO:0008736 IPR005763
GO:0030145 IPR005763
GO:0019317 IPR005763
GO:0005737 IPR005763

0 Parent Features

0 Proteins

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9367760