Type: | Domain | Name: | L-fucose/L-arabinose isomerase, C-terminal |
Description: | L-fucose isomerase () converts the aldose L-fucose into the corresponding ketose L-fuculose during the first step in fucose metabolism using Mn2+ as a cofactor. The enzyme is a hexamer, forming the largest structurally known ketol isomerase, and has no sequence or structural similarity with other ketol isomerases. The structure was determined by X-ray crystallography at 2.5 A resolution []. L-arabinose isomerase (AraA) () catalyses the conversion of L-arabinose to L-ribulose as the first step in the pathway of L-arabinose utilization as a carbon source [].L-arabinose isomerase adopts a protein fold most similar to fucose isomerase despite low sequence identity []. This entry represents a C-terminal structural domain common to L-fucose and L-arabinose isomerases. | Short Name: | Fuc/Ara_isomerase_C |