Protein Domain : IPR006478

Type:  Family Name:  Formate dehydrogenase, alpha subunit
Description:  This group of sequences describe a subset of formate dehydrogenase alpha chains found mainly in the archaea but also in alpha and gamma proteobacteria and a small number of Gram-positive bacteria. The alpha chain contains domains for molybdopterin dinucleotide binding and molybdopterin oxidoreductase. The holo-enzyme also contains beta and gamma subunits. The enzyme catalyzes the oxidation of formate (produced from pyruvate during anaerobic growth) to carbon dioxide with the concomitant release of two electrons and two protons. The enzyme's purpose is to allow growth on formate in some circumstances [] and, in the case of FdhH in gamma proteobacteria, to pass electrons to hydrogenase (by which process acid is neutralized) []. The alpha subunit of a version of nitrate reductase is closely related. Short Name:  Formate_DH_asu
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0 Child Features

4 Contains

DB identifier Type Name
IPR006963 Domain Molybdopterin oxidoreductase, 4Fe-4S domain
IPR006656 Domain Molybdopterin oxidoreductase
IPR006657 Domain Molybdopterin dinucleotide-binding domain
IPR006655 Conserved_site Molybdopterin oxidoreductase, prokaryotic, conserved site

2 Cross Referencess

Identifier
PIRSF036643
TIGR01591

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0008863 IPR006478
GO:0015942 IPR006478
GO:0055114 IPR006478

3 Ontology Annotations

GO Term Gene Name
GO:0008863 IPR006478
GO:0015942 IPR006478
GO:0055114 IPR006478

0 Parent Features

1 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
31326.m000015 B9TCR2 PAC:16824948 Ricinus communis 588  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            3531194
            9036855