| Type: | Domain | Name: | Pyruvate-flavodoxin oxidoreductase, central domain |
| Description: | This domain is found in prokaryotes. It includes a region of the large protein pyruvate-flavodoxin oxidoreductase and the whole pyruvate ferredoxin oxidoreductase gamma subunit protein. It is not known whether the gamma subunit has a catalytic or regulatory role. Pyruvateoxidoreductase (POR) catalyses the final step in the fermentation of carbohydrates in anaerobic microorganisms []. This involves theoxidative decarboxylation of pyruvate with the participation of thiamine followed by the transfer of an acetyl moiety to coenzymeA for the synthesis of acetyl-CoA []. The family also includespyruvate flavodoxin oxidoreductase as encoded by the nifJ gene in cyanobacterium which is required for growth on molecular nitrogenwhen iron is limited []. | Short Name: | Pyrv_flavodox_OxRed_cen |
