GO Term : GO:0004602 glutathione peroxidase activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the reaction: 2 glutathione + hydrogen peroxide = oxidized glutathione + 2 H2O.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0004602 228619  
OntologyAnnotation GO:0004602 228619 GO
GOAnnotation GO:0004602 140057  
OntologyAnnotation GO:0004602 140057 GO
GOAnnotation GO:0004602 75178  
OntologyAnnotation GO:0004602 75178 GO
OntologyAnnotation GO:0004602 97488 GO
GOAnnotation GO:0004602 97488  
OntologyAnnotation GO:0004602 78732 GO
GOAnnotation GO:0004602 78732  
OntologyAnnotation GO:0004602 evm.TU.contig_32791.1 GO
GOAnnotation GO:0004602 evm.TU.contig_32791  
GOAnnotation GO:0004602 evm.TU.supercontig_148.23  
OntologyAnnotation GO:0004602 evm.model.supercontig_148.23 GO
GOAnnotation GO:0004602 evm.TU.supercontig_71.15  
OntologyAnnotation GO:0004602 evm.model.supercontig_71.15 GO
GOAnnotation GO:0004602 evm.TU.supercontig_74.22  
OntologyAnnotation GO:0004602 evm.model.supercontig_74.21 GO
GOAnnotation GO:0004602 evm.TU.supercontig_74.21  
OntologyAnnotation GO:0004602 evm.model.supercontig_74.22 GO
GOAnnotation GO:0004602 evm.TU.supercontig_837.1  
OntologyAnnotation GO:0004602 evm.model.supercontig_837.1 GO
GOAnnotation GO:0004602 28153.t000012  
OntologyAnnotation GO:0004602 28153.m000283 GO
OntologyAnnotation GO:0004602 29657.m000470 GO
GOAnnotation GO:0004602 29657.t000011  
OntologyAnnotation GO:0004602 29848.m004526 GO
GOAnnotation GO:0004602 29848.t000082  
OntologyAnnotation GO:0004602 30190.m011204 GO
GOAnnotation GO:0004602 30190.t000441  

19 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0004601 peroxidase activity Catalysis of the reaction: donor + hydrogen peroxide = oxidized donor + 2 H2O.
GO:0004602 glutathione peroxidase activity Catalysis of the reaction: 2 glutathione + hydrogen peroxide = oxidized glutathione + 2 H2O.
GO:0016209 antioxidant activity Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0009636 response to toxic substance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0098869 cellular oxidant detoxification Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0044710 single-organism metabolic process A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
GO:0098754 detoxification Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
GO:0016684 oxidoreductase activity, acting on peroxide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which the peroxide group acts as a hydrogen or electron acceptor.
GO:1990748 cellular detoxification Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.

26 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0004601 GO:0004602
part of GO:0055114 GO:0004602
part of GO:0009636 GO:0004602
part of GO:0009987 GO:0004602
is_a GO:0016684 GO:0004602
part of GO:0050896 GO:0004602
is_a GO:0003674 GO:0004602
part of GO:0098754 GO:0004602
is_a GO:0016491 GO:0004602
is_a GO:0003824 GO:0004602
part of GO:0098869 GO:0004602
part of GO:0042221 GO:0004602
part of GO:1990748 GO:0004602
part of GO:0008150 GO:0004602
part of GO:0008152 GO:0004602
is_a GO:0016209 GO:0004602
part of GO:0044710 GO:0004602
part of GO:0044699 GO:0004602
regulates GO:0004602 GO:1903282
regulates GO:0004602 GO:1903282
negatively regulates GO:0004602 GO:1903283
negatively regulates GO:0004602 GO:1903283
regulates GO:0004602 GO:1903283
positively regulates GO:0004602 GO:1903284
positively regulates GO:0004602 GO:1903284
regulates GO:0004602 GO:1903284

6 Synonyms

Name Type
reduced glutathione peroxidase activity synonym
non-selenium glutathione peroxidase activity synonym
GO:0016224 alt_id
selenium-glutathione peroxidase activity synonym
GSH peroxidase activity synonym
glutathione:hydrogen-peroxide oxidoreductase activity synonym