GO Term : GO:0004362 glutathione-disulfide reductase activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the reaction: 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0004362 164085  
OntologyAnnotation GO:0004362 164085 GO
GOAnnotation GO:0004362 438142  
OntologyAnnotation GO:0004362 438142 GO
OntologyAnnotation GO:0004362 evm.model.supercontig_52.87 GO
GOAnnotation GO:0004362 evm.TU.supercontig_52.87  
GOAnnotation GO:0004362 evm.TU.supercontig_59.122  
OntologyAnnotation GO:0004362 evm.model.supercontig_59.122 GO
OntologyAnnotation GO:0004362 29883.m001999 GO
GOAnnotation GO:0004362 29883.t000054  
OntologyAnnotation GO:0004362 29904.m002966 GO
GOAnnotation GO:0004362 29904.t000080  
GOAnnotation GO:0004362 Cucsa.256350  
OntologyAnnotation GO:0004362 Cucsa.256350.1 GO
OntologyAnnotation GO:0004362 Cucsa.256350.2 GO
OntologyAnnotation GO:0004362 Cucsa.256350.3 GO
OntologyAnnotation GO:0004362 Cucsa.388700.2 GO
GOAnnotation GO:0004362 Cucsa.388700  
OntologyAnnotation GO:0004362 Cucsa.388700.1 GO
OntologyAnnotation GO:0004362 orange1.1g042564m GO
GOAnnotation GO:0004362 orange1.1g042564m.g  
GOAnnotation GO:0004362 orange1.1g008841m.g  
OntologyAnnotation GO:0004362 orange1.1g008860m GO
OntologyAnnotation GO:0004362 orange1.1g008839m GO
OntologyAnnotation GO:0004362 orange1.1g008841m GO
GOAnnotation GO:0004362 AT3G24170  
OntologyAnnotation GO:0004362 AT3G24170.1 GO
OntologyAnnotation GO:0004362 AT3G24170.2 GO
OntologyAnnotation GO:0004362 AT3G24170.3 GO
GOAnnotation GO:0004362 AT3G54660  

23 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0016209 antioxidant activity Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0004362 glutathione-disulfide reductase activity Catalysis of the reaction: 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+.
GO:0016651 oxidoreductase activity, acting on NAD(P)H Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0009636 response to toxic substance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces NAD or NADP.
GO:0098869 cellular oxidant detoxification Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0044710 single-organism metabolic process A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
GO:0016667 oxidoreductase activity, acting on a sulfur group of donors Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0098754 detoxification Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
GO:1990748 cellular detoxification Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
GO:0015038 glutathione disulfide oxidoreductase activity Catalysis of the reaction: 2 glutathione + electron acceptor = glutathione disulfide + electron donor.
GO:0015037 peptide disulfide oxidoreductase activity Catalysis of the reaction: a peptide with reduced sulfide groups = a peptide with oxidized disulfide bonds.
GO:0015036 disulfide oxidoreductase activity Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds.

22 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0015038 GO:0004362
is_a GO:0016209 GO:0004362
is_a GO:0016668 GO:0004362
part of GO:0050896 GO:0004362
part of GO:0098754 GO:0004362
is_a GO:0016667 GO:0004362
part of GO:0098869 GO:0004362
part of GO:0042221 GO:0004362
is_a GO:0015037 GO:0004362
is_a GO:0016651 GO:0004362
is_a GO:0015036 GO:0004362
part of GO:0008150 GO:0004362
part of GO:0008152 GO:0004362
is_a GO:0016491 GO:0004362
is_a GO:0003824 GO:0004362
part of GO:0044710 GO:0004362
part of GO:0044699 GO:0004362
part of GO:1990748 GO:0004362
part of GO:0009987 GO:0004362
part of GO:0055114 GO:0004362
part of GO:0009636 GO:0004362
is_a GO:0003674 GO:0004362

11 Synonyms

Name Type
oxidized glutathione reduction synonym
NADPH-glutathione reductase activity synonym
NADPH-GSSG reductase activity synonym
NADPH:oxidized-glutathione oxidoreductase activity synonym
glutathione reductase (NADPH) activity synonym
glutathione reductase activity synonym
glutathione S-reductase activity synonym
glutathione-disulphide reductase activity synonym
glutathione:NADP+ oxidoreductase activity synonym
GSH reductase activity synonym
GSSG reductase activity synonym