GO Term : GO:0005852 eukaryotic translation initiation factor 3 complex GO

Namespace:  cellular_component Obsolete:  false
description  A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
OntologyAnnotation GO:0005852 233382 GO
GOAnnotation GO:0005852 233382  
GOAnnotation GO:0005852 153526  
OntologyAnnotation GO:0005852 153526 GO
GOAnnotation GO:0005852 154794  
OntologyAnnotation GO:0005852 154794 GO
GOAnnotation GO:0005852 118934  
OntologyAnnotation GO:0005852 118934 GO
OntologyAnnotation GO:0005852 446105 GO
GOAnnotation GO:0005852 446105  
GOAnnotation GO:0005852 125074  
OntologyAnnotation GO:0005852 125074 GO
OntologyAnnotation GO:0005852 87880 GO
GOAnnotation GO:0005852 87880  
GOAnnotation GO:0005852 269321  
OntologyAnnotation GO:0005852 269321 GO
GOAnnotation GO:0005852 437467  
OntologyAnnotation GO:0005852 437467 GO
GOAnnotation GO:0005852 146079  
OntologyAnnotation GO:0005852 146079 GO
GOAnnotation GO:0005852 269977  
OntologyAnnotation GO:0005852 269977 GO
OntologyAnnotation GO:0005852 152189 GO
GOAnnotation GO:0005852 152189  
OntologyAnnotation GO:0005852 evm.model.supercontig_119.20 GO
GOAnnotation GO:0005852 evm.TU.supercontig_119.20  
GOAnnotation GO:0005852 evm.TU.supercontig_17.146  
OntologyAnnotation GO:0005852 evm.model.supercontig_17.146 GO
GOAnnotation GO:0005852 evm.TU.supercontig_178.2  
OntologyAnnotation GO:0005852 evm.model.supercontig_178.2 GO

10 Parents

Identifier Name Description
GO:0005737 cytoplasm All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0043234 protein complex A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
GO:0005622 intracellular The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0005852 eukaryotic translation initiation factor 3 complex A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0044444 cytoplasmic part Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0044424 intracellular part Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0032991 macromolecular complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

14 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0044444 GO:0005852
is_a GO:0043234 GO:0005852
part of GO:0005622 GO:0005852
part of GO:0005623 GO:0005852
part of GO:0005737 GO:0005852
is_a GO:0044424 GO:0005852
is_a GO:0005575 GO:0005852
part of GO:0044464 GO:0005852
is_a GO:0044464 GO:0005852
is_a GO:0032991 GO:0005852
part of GO:0044424 GO:0005852
part of GO:0005575 GO:0005852
is_a GO:0005852 GO:0071540
is_a GO:0005852 GO:0071541

2 Synonyms

Name Type
eIF3 synonym
eIF-3 synonym