GO Term : GO:0043564 Ku70:Ku80 complex GO

Namespace:  cellular_component Obsolete:  false
description  Heterodimeric protein complex composed of a 70 kDa and a 80 kDa subunit, binds DNA through a channel formed by the heterodimer. Functions in DNA double stranded break repair, chromosome maintenance, transcription regulation, V(D)J recombination, and activation of DNA-PK.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0043564 74928  
OntologyAnnotation GO:0043564 74928 GO
GOAnnotation GO:0043564 165509  
OntologyAnnotation GO:0043564 165509 GO
GOAnnotation GO:0043564 78255  
OntologyAnnotation GO:0043564 78255 GO
GOAnnotation GO:0043564 evm.TU.supercontig_18.115  
OntologyAnnotation GO:0043564 evm.model.supercontig_18.115 GO
GOAnnotation GO:0043564 evm.TU.supercontig_77.50  
OntologyAnnotation GO:0043564 evm.model.supercontig_77.50 GO
GOAnnotation GO:0043564 29634.t000033  
OntologyAnnotation GO:0043564 29634.m002087 GO
OntologyAnnotation GO:0043564 Cucsa.094430.1 GO
GOAnnotation GO:0043564 Cucsa.094430  
OntologyAnnotation GO:0043564 Cucsa.094430.2 GO
OntologyAnnotation GO:0043564 Cucsa.094430.3 GO
GOAnnotation GO:0043564 orange1.1g006975m.g  
OntologyAnnotation GO:0043564 orange1.1g006975m GO
GOAnnotation GO:0043564 AT1G16970  
OntologyAnnotation GO:0043564 AT1G16970.1 GO
GOAnnotation GO:0043564 Thhalv10007085m.g  
OntologyAnnotation GO:0043564 Thhalv10007085m GO
OntologyAnnotation GO:0043564 Ciclev10019318m GO
GOAnnotation GO:0043564 Ciclev10019318m.g  
OntologyAnnotation GO:0043564 Lus10015868 GO
GOAnnotation GO:0043564 Lus10015868.g  
OntologyAnnotation GO:0043564 Lus10005783 GO
GOAnnotation GO:0043564 Lus10005783.g  
OntologyAnnotation GO:0043564 Lus10006818 GO
GOAnnotation GO:0043564 Lus10006818.g  

16 Parents

Identifier Name Description
GO:0005634 nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
GO:0043234 protein complex A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
GO:0005622 intracellular The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0043231 intracellular membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GO:0043564 Ku70:Ku80 complex Heterodimeric protein complex composed of a 70 kDa and a 80 kDa subunit, binds DNA through a channel formed by the heterodimer. Functions in DNA double stranded break repair, chromosome maintenance, transcription regulation, V(D)J recombination, and activation of DNA-PK.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0044424 intracellular part Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0032991 macromolecular complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0044428 nuclear part Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated.
GO:0043227 membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GO:0043226 organelle Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
GO:0043229 intracellular organelle Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0044422 organelle part Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
GO:0044446 intracellular organelle part A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

18 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0044428 GO:0043564
is_a GO:0043234 GO:0043564
part of GO:0043229 GO:0043564
part of GO:0043227 GO:0043564
part of GO:0043226 GO:0043564
part of GO:0044424 GO:0043564
part of GO:0044464 GO:0043564
part of GO:0043231 GO:0043564
is_a GO:0032991 GO:0043564
part of GO:0005634 GO:0043564
part of GO:0005623 GO:0043564
part of GO:0005622 GO:0043564
part of GO:0005575 GO:0043564
is_a GO:0044464 GO:0043564
is_a GO:0005575 GO:0043564
is_a GO:0044446 GO:0043564
is_a GO:0044424 GO:0043564
is_a GO:0044422 GO:0043564

1 Synonyms

Name Type
Ku70:Ku80 heterodimer synonym