GO Term : GO:0004512 inositol-3-phosphate synthase activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0004512 270269  
OntologyAnnotation GO:0004512 270269 GO
GOAnnotation GO:0004512 evm.TU.supercontig_557.2  
OntologyAnnotation GO:0004512 evm.model.supercontig_557.2 GO
GOAnnotation GO:0004512 28205.t000002  
OntologyAnnotation GO:0004512 28205.m000068 GO
GOAnnotation GO:0004512 Cucsa.029470  
OntologyAnnotation GO:0004512 Cucsa.029470.1 GO
GOAnnotation GO:0004512 Cucsa.104560  
OntologyAnnotation GO:0004512 Cucsa.104560.1 GO
OntologyAnnotation GO:0004512 orange1.1g043178m GO
GOAnnotation GO:0004512 orange1.1g043178m.g  
OntologyAnnotation GO:0004512 orange1.1g011047m GO
OntologyAnnotation GO:0004512 orange1.1g010460m GO
GOAnnotation GO:0004512 orange1.1g010460m.g  
GOAnnotation GO:0004512 AT2G22240  
OntologyAnnotation GO:0004512 AT2G22240.2 GO
OntologyAnnotation GO:0004512 AT2G22240.1 GO
OntologyAnnotation GO:0004512 AT4G39800.1 GO
GOAnnotation GO:0004512 AT4G39800  
OntologyAnnotation GO:0004512 AT5G10170.1 GO
GOAnnotation GO:0004512 AT5G10170  
GOAnnotation GO:0004512 Thhalv10025200m.g  
OntologyAnnotation GO:0004512 Thhalv10025200m GO
GOAnnotation GO:0004512 Thhalv10000134m.g  
OntologyAnnotation GO:0004512 Thhalv10000134m GO
GOAnnotation GO:0004512 Thhalv10015635m.g  
OntologyAnnotation GO:0004512 Thhalv10015635m GO
OntologyAnnotation GO:0004512 Ciclev10025400m GO
GOAnnotation GO:0004512 Ciclev10025400m.g  

7 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0016853 isomerase activity Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
GO:0004512 inositol-3-phosphate synthase activity Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.
GO:0016872 intramolecular lyase activity The catalysis of certain rearrangements of a molecule to break or form a ring.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

6 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0016872 GO:0004512
part of GO:0008150 GO:0004512
is_a GO:0003674 GO:0004512
is_a GO:0016853 GO:0004512
part of GO:0008152 GO:0004512
is_a GO:0003824 GO:0004512

7 Synonyms

Name Type
D-glucose 6-phosphate cycloaldolase activity synonym
1L-myo-inositol-1-phosphate lyase (isomerizing) synonym
glucose 6-phosphate cyclase activity synonym
glucocycloaldolase activity synonym
inositol 1-phosphate synthatase activity synonym
glucose-6-phosphate inositol monophosphate cycloaldolase activity synonym
inositol 1-phosphate synthetase activity synonym