GO Term : GO:0003917 DNA topoisomerase type I activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0003917 19423  
OntologyAnnotation GO:0003917 19426 GO
OntologyAnnotation GO:0003917 19423 GO
GOAnnotation GO:0003917 19426  
GOAnnotation GO:0003917 168492  
OntologyAnnotation GO:0003917 168492 GO
GOAnnotation GO:0003917 123748  
OntologyAnnotation GO:0003917 123748 GO
GOAnnotation GO:0003917 145504  
OntologyAnnotation GO:0003917 145504 GO
OntologyAnnotation GO:0003917 5960 GO
GOAnnotation GO:0003917 5960  
OntologyAnnotation GO:0003917 410336 GO
GOAnnotation GO:0003917 410336  
GOAnnotation GO:0003917 410935  
OntologyAnnotation GO:0003917 410935 GO
OntologyAnnotation GO:0003917 5961 GO
GOAnnotation GO:0003917 5961  
OntologyAnnotation GO:0003917 94303 GO
GOAnnotation GO:0003917 94303  
OntologyAnnotation GO:0003917 417843 GO
GOAnnotation GO:0003917 417843  
GOAnnotation GO:0003917 109207  
OntologyAnnotation GO:0003917 109207 GO
OntologyAnnotation GO:0003917 152781 GO
GOAnnotation GO:0003917 152781  
OntologyAnnotation GO:0003917 evm.model.supercontig_107.55 GO
GOAnnotation GO:0003917 evm.TU.supercontig_107.55  
GOAnnotation GO:0003917 evm.TU.supercontig_12.228  
OntologyAnnotation GO:0003917 evm.model.supercontig_12.228 GO

12 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0003677 DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0003676 nucleic acid binding Interacting selectively and non-covalently with any nucleic acid.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0016853 isomerase activity Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
GO:0003917 DNA topoisomerase type I activity Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.
GO:0003916 DNA topoisomerase activity Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:1901363 heterocyclic compound binding Interacting selectively and non-covalently with heterocyclic compound.
GO:0097159 organic cyclic compound binding Interacting selectively and non-covalently with an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure.

12 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0003916 GO:0003917
part of GO:0008152 GO:0003917
has_part GO:1901363 GO:0003917
has_part GO:0097159 GO:0003917
is_a GO:0003674 GO:0003917
is_a GO:0016853 GO:0003917
is_a GO:0003824 GO:0003917
has_part GO:0003674 GO:0003917
has_part GO:0003677 GO:0003917
has_part GO:0003676 GO:0003917
has_part GO:0005488 GO:0003917
part of GO:0008150 GO:0003917

10 Synonyms

Name Type
type I topoisomerase activity synonym
type I DNA topoisomerase activity synonym
untwisting enzyme activity synonym
deoxyribonucleate topoisomerase synonym
DNA topoisomerase I activity synonym
omega-protein activity synonym
topoisomerase synonym
nicking-closing enzyme activity synonym
swivelase activity synonym
relaxing enzyme activity synonym