GO Term : GO:0016255 attachment of GPI anchor to protein GO

Namespace:  biological_process Obsolete:  false
description  A transamidation reaction that results in the cleavage of the polypeptide chain and the concomitant transfer of the GPI anchor to the newly formed carboxy-terminal amino acid of the anchored protein. The cleaved C-terminal contains the C-terminal GPI signal sequence of the newly synthesized polypeptide chain.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0016255 82177  
OntologyAnnotation GO:0016255 82177 GO
GOAnnotation GO:0016255 439141  
OntologyAnnotation GO:0016255 439141 GO
GOAnnotation GO:0016255 422871  
OntologyAnnotation GO:0016255 422871 GO
OntologyAnnotation GO:0016255 133060 GO
GOAnnotation GO:0016255 133060  
GOAnnotation GO:0016255 429515  
OntologyAnnotation GO:0016255 429514 GO
GOAnnotation GO:0016255 429514  
OntologyAnnotation GO:0016255 429516 GO
GOAnnotation GO:0016255 429516  
OntologyAnnotation GO:0016255 429515 GO
OntologyAnnotation GO:0016255 429556 GO
GOAnnotation GO:0016255 429556  
OntologyAnnotation GO:0016255 429558 GO
GOAnnotation GO:0016255 429558  
OntologyAnnotation GO:0016255 448334 GO
GOAnnotation GO:0016255 448334  
OntologyAnnotation GO:0016255 432081 GO
GOAnnotation GO:0016255 432081  
OntologyAnnotation GO:0016255 432084 GO
GOAnnotation GO:0016255 432084  
OntologyAnnotation GO:0016255 432082 GO
GOAnnotation GO:0016255 432082  
OntologyAnnotation GO:0016255 449314 GO
GOAnnotation GO:0016255 449314  
OntologyAnnotation GO:0016255 432085 GO
GOAnnotation GO:0016255 432085  

50 Parents

Identifier Name Description
GO:0006629 lipid metabolic process The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
GO:0008654 phospholipid biosynthetic process The chemical reactions and pathways resulting in the formation of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
GO:0006796 phosphate-containing compound metabolic process The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0008610 lipid biosynthetic process The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
GO:0006506 GPI anchor biosynthetic process The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
GO:0019538 protein metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
GO:0006505 GPI anchor metabolic process The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain.
GO:0006464 cellular protein modification process The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0016255 attachment of GPI anchor to protein A transamidation reaction that results in the cleavage of the polypeptide chain and the concomitant transfer of the GPI anchor to the newly formed carboxy-terminal amino acid of the anchored protein. The cleaved C-terminal contains the C-terminal GPI signal sequence of the newly synthesized polypeptide chain.
GO:0043412 macromolecule modification The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.
GO:0006661 phosphatidylinositol biosynthetic process The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
GO:0046488 phosphatidylinositol metabolic process The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0006644 phospholipid metabolic process The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester.
GO:0045017 glycerolipid biosynthetic process The chemical reactions and pathways resulting in the formation of glycerolipids, any lipid with a glycerol backbone.
GO:1901137 carbohydrate derivative biosynthetic process The chemical reactions and pathways resulting in the formation of carbohydrate derivative.
GO:0044249 cellular biosynthetic process The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GO:0009059 macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0009247 glycolipid biosynthetic process The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide).
GO:0006650 glycerophospholipid metabolic process The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
GO:0044260 cellular macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0044267 cellular protein metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0042158 lipoprotein biosynthetic process The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.
GO:0006793 phosphorus metabolic process The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).
GO:0044255 cellular lipid metabolic process The chemical reactions and pathways involving lipids, as carried out by individual cells.

62 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0006506 GO:0016255
is_a GO:0006464 GO:0016255
part of GO:0019637 GO:0016255
part of GO:0036211 GO:0016255
part of GO:0044237 GO:0016255
part of GO:0044710 GO:0016255
part of GO:0044238 GO:0016255
part of GO:0044711 GO:0016255
is_a GO:0071704 GO:0016255
is_a GO:0008150 GO:0016255
part of GO:0006644 GO:0016255
is_a GO:0008152 GO:0016255
part of GO:0006643 GO:0016255
part of GO:0046467 GO:0016255
is_a GO:0036211 GO:0016255
part of GO:0071704 GO:0016255
part of GO:0043412 GO:0016255
part of GO:0008610 GO:0016255
part of GO:0008654 GO:0016255
part of GO:0009987 GO:0016255
part of GO:0006629 GO:0016255
part of GO:0006505 GO:0016255
part of GO:0006796 GO:0016255
part of GO:1901137 GO:0016255
part of GO:1901135 GO:0016255
part of GO:0006793 GO:0016255
part of GO:1901576 GO:0016255
part of GO:0090407 GO:0016255
part of GO:0019538 GO:0016255
part of GO:0042157 GO:0016255

0 Synonyms